• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ASGR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201737

This is a rabbit polyclonal antibody against ASGR2. It was validated on Western Blot and immunohistochemistryTarget Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical… More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASGR2, Polyclonal Antibody
Full Product Name
ASGR2 antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
Immunogen Sequence
Synthetic peptide located within the following region: LVVICVTGSQ SEGHRGAQLQ AELRSLKEAF SNFSSSTLTE VQAISTHGGS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Pig, Rat, Yeast
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ASGR2 peptide (MBS3226740) is used for blocking the activity of ASGR2 antibody (MBS3201737)
Molecular Weight
35kDa
OMIM
108361
3D Structure
ModBase 3D Structure for P07307
Homology
Human: 100%; Pig: 77%; Rat: 79%; Yeast: 77%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2
Applications Tested/Suitable for anti-ASGR2 antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-ASGR2 antibody

Human Intestine
Rabbit Anti-ASGR2 Polyclonal Antibody – Cat# MBS3201737

Immunohistochemistry (IHC) of anti-ASGR2 antibody

Rabbit Anti-ANKRD12 Antibody
Paraffin Embedded Tissue: Human cilia
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Rabbit Anti-ASGR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS3201737

Western Blot (WB) of anti-ASGR2 antibody

WB Suggested Anti-ASGR2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Lung
Rabbit Anti-ASGR2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201737

Other Notes

Small volumes of anti-ASGR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASGR2 purchase

MBS3201737 is an antibody targeting ASGR2. Also known as ASGR2 antibody - N-terminal region. Reactive in Human, Pig, Rat, Yeast. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASGR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
asialoglycoprotein receptor 2 isoform a
NCBI Official Synonym Full Names
asialoglycoprotein receptor 2
NCBI Official Symbol
ASGR2
NCBI Official Synonym Symbols
HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
UniProt Protein Name
Asialoglycoprotein receptor 2
UniProt Synonym Protein Names
C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
UniProt Gene Name
ASGR2
UniProt Synonym Gene Names
CLEC4H2; ASGP-R 2; ASGPR 2; HL-2
UniProt Entry Name
ASGR2_HUMAN
NCBI Protein Information
asialoglycoprotein receptor 2

NCBI Summary for ASGR2

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Show more

UniProt Comments for ASGR2

ASGP-R: cell surface receptor that mediates the endocytosis of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p

Cellular Component: integral to membrane

Molecular Function: protein binding; asialoglycoprotein receptor activity; carbohydrate binding

Biological Process: receptor-mediated endocytosis; cell surface receptor linked signal transduction; glycoprotein metabolic process; lipid homeostasis; regulation of protein stability; bone mineralization
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ASGR2 antibody

 Reference Product  PubMed Publications
 ASGR1 antibody  >3 publications with ASGR2 and ASGR1

Diseases associated with anti-ASGR2 antibody

 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >1 publications with ASGR2 and Hepatitis

Organs/Tissues associated with anti-ASGR2 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000