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FMOD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7051949

Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FMOD, Polyclonal Antibody
Full Product Name
FMOD Antibody
Product Gene Name
Product Synonym Names
Fibromodulin; FM; Collagen-binding 59 kDa protein; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; FMOD; FM; SLRR2E
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: FMOD (MBS7051949)
HRP Conjugated Antibody: FMOD (MBS7051950)
Matching Pairs
Unconjugated Antibody: FMOD (MBS7051949)
FITC Conjugated Antibody: FMOD (MBS7051951)
Molecular Weight
43,179 Da
OMIM
X72913 Genomic DNA
3D Structure
ModBase 3D Structure for Q06828
Immunogen
Recombinant Human Fibromodulin protein (18-89AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FMOD antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FMOD antibody
WB: 1:500-1:5000
IHC: 1:20-1:200

Western Blot (WB) of anti-FMOD antibody

Western Blot
Positive WB detected in: A549 whole cell lysate,MCF-7 whole cell lysate,Rat liver tissue
All lanes: FMOD antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 44 KDa
Observed band size: 44 KDa
Rabbit Anti-FMOD Polyclonal Antibody – Cat# MBS7051949

Immunohistochemistry (IHC) of anti-FMOD antibody

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7051949 at dilution of 1:100
Rabbit Anti-FMOD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7051949

Immunohistochemistry (IHC) of anti-FMOD antibody

Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS7051949 at dilution of 1:100
Rabbit Anti-FMOD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7051949

Other Notes

Small volumes of anti-FMOD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FMOD purchase

MBS7051949 is an antibody targeting FMOD. Also known as FMOD Antibody. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FMOD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibromodulin
NCBI Official Synonym Full Names
fibromodulin
NCBI Official Symbol
FMOD
NCBI Official Synonym Symbols
FM; SLRR2E
UniProt Protein Name
Fibromodulin
UniProt Synonym Protein Names
Collagen-binding 59 kDa protein; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
Protein Family
UniProt Gene Name
FMOD
UniProt Synonym Gene Names
FM; SLRR2E; FM; KSPG fibromodulin
NCBI Protein Information
fibromodulin

NCBI Summary for FMOD

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
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UniProt Comments for FMOD

FMOD: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: extracellular matrix; extracellular region; extracellular space; Golgi lumen; lysosomal lumen

Molecular Function: heparin binding; Roundabout binding

Biological Process: axon extension involved in axon guidance; axonogenesis; keratan sulfate biosynthetic process; keratan sulfate catabolic process; regulation of axonogenesis; transforming growth factor beta receptor complex assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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