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MCMBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2561184

This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MCMBP, Polyclonal Antibody
Full Product Name
MCMBP Polyclonal Antibody
Product Gene Name
anti-MCMBP antibody
Product Synonym Names
C10orf119; Chromosome 10 open reading frame 119; MCM-binding protein; MCM-BP; Mcmbp; MCMBP; Mini-chromosome maintenance complex-binding protein; Minichromosome maintenance complex binding protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.96mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
73 kDa
OMIM
610909
3D Structure
ModBase 3D Structure for Q9BTE3
Immunogen
Synthetic peptide of human MCMBP
Conjugation
Unconjugated

Product Categories/Family for anti-MCMBP antibody

Cell Biology; Epigenetics and Nuclear Signaling
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MCMBP antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MCMBP antibody
WB: 1:500-1:2000
IHC: 1:30-1:150
ELISA: 1:5000-1:10000

Western Blot (WB) of anti-MCMBP antibody

Western blot analysis of 293T cell lysate using MCMBP Polyclonal Antibody at dilution of 1:800
Rabbit Anti-MCMBP Polyclonal Antibody – Cat# MBS2561184

Immunohistochemistry (IHC) of anti-MCMBP antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MCMBP Polyclonal Antibody at dilution of 1:35(×200)
Rabbit Anti-MCMBP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2561184

Immunohistochemistry (IHC) of anti-MCMBP antibody

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MCMBP Polyclonal Antibody at dilution of 1:35(×200)
Rabbit Anti-MCMBP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2561184

Other Notes

Small volumes of anti-MCMBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCMBP purchase

MBS2561184 is an antibody targeting MCMBP. Also known as MCMBP Polyclonal Antibody. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MCMBP. It may not necessarily be applicable to this product.

NCBI GI #
71153001
NCBI GeneID
79892
NCBI Accession #
Q9BTE3.2
UniProt Primary Accession #
Q9BTE3
NCBI Official Full Name
Mini-chromosome maintenance complex-binding protein
UniProt Protein Name
Mini-chromosome maintenance complex-binding protein
Protein Family
Mini-chromosome maintenance complex-binding protein
UniProt Gene Name
MCMBP
UniProt Synonym Gene Names
C10orf119; MCM-BP; MCM-binding protein
UniProt Entry Name
MCMBP_HUMAN

UniProt Comments for MCMBP

MCMBP: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. Belongs to the MCMBP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 10q26.11

Cellular Component: nucleoplasm; MCM complex; cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; chromatin binding

Biological Process: mitosis; cell division; sister chromatid cohesion; DNA-dependent DNA replication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MCMBP antibody

 Reference Product  PubMed Publications
 MCM7 antibody  >3 publications with MCMBP and MCM7
 MCM2 antibody  >2 publications with MCMBP and MCM2
 MCM6 antibody  >2 publications with MCMBP and MCM6
 MCM4 antibody  >2 publications with MCMBP and MCM4
 USP7 antibody  >1 publications with MCMBP and USP7
 MCM5 antibody  >1 publications with MCMBP and MCM5
 MCM3 antibody  >1 publications with MCMBP and MCM3

Diseases associated with anti-MCMBP antibody

 Disease Name  Pubmed Publications
 Uterine Cervical Neoplasms Antibodies  >1 publications with MCMBP and Uterine Cervical Neoplasms
 Breast Neoplasms Antibodies  >1 publications with MCMBP and Breast Neoplasms
 Inflammation Antibodies  >1 publications with MCMBP and Inflammation

Organs/Tissues associated with anti-MCMBP antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with MCMBP and Vascular
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