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IGHA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9202815

MBS9202815 is an antibody targeting IGHA1. Also known as IGH Antibody (C-Term). Reactive in Human. Host: Rabbit. More details

$240 / 0.08 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IGH (IGHA1), Polyclonal Antibody
Full Product Name
IGH Antibody (C-Term)
Product Gene Name
Product Synonym Names
Ig alpha-1 chain C region; IGHA1
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.326 (lot specific)
Specificity
This IGH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from the C-terminal region of human IGH.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
IGH peptide (MBS9227846) is used for blocking the activity of IGH antibody (MBS9202815)
Molecular Weight
37655
Immunogen Sequence Positions
290-320
OMIM
146900
3D Structure
ModBase 3D Structure for P01876
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-IGHA1 antibody

Applications Tested/Suitable for anti-IGHA1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-IGHA1 antibody
WB~~1:1000

Western Blot (WB) of anti-IGHA1 antibody

Western blot analysis of IGH Antibody (C-Term) in HL-60, A2058 cell line lysates (35ug/lane). IGH (arrow) was detected using the purified Pab.
Rabbit Anti-IGHA1 Polyclonal Antibody – Cat# MBS9202815

Immunohistochemistry (IHC) of anti-IGHA1 antibody

Formalin-fixed and paraffin-embedded human skin reacted with IGH Antibody (C-Term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-IGHA1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9202815

Flow Cytometry (FC/FACS) of anti-IGHA1 antibody

IGH Antibody (C-Term) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-IGHA1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS9202815

Product References and Citations for anti-IGHA1 antibody

Strausberg,R.L.,et.al., Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)

Other Notes

Small volumes of anti-IGHA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGHA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Ig alpha-1 chain C region
UniProt Protein Name
Ig alpha-1 chain C region
UniProt Gene Name
IGHA1
UniProt Entry Name
IGHA1_HUMAN

UniProt Comments for IGHA1

IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.

Protein type: Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IGHA1 antibody

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