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ASAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6275495

Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling… More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASAP1, Polyclonal Antibody
Full Product Name
ASAP1, ID (ASAP1, DDEF1, KIAA1249, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130kD phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1
Product Gene Name
Product Synonym Names
ASAP1; DDEF1; KIAA1249; Arf-GAP with SH3 domain; ANK repeat and PH domain-containing protein 1; 130kD phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; Development and differentiation-enhancing factor 1; PIP2-dependent ARF1 GAP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
125,897 Da
OMIM
605953
3D Structure
ModBase 3D Structure for Q9ULH1
Immunogen
ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the Central region of human ASAP1.
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-ASAP1 antibody

Applications Tested/Suitable for anti-ASAP1 antibody
Western Blot (WB), FLISA
Application Notes for anti-ASAP1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-ASAP1 antibody

Muller, T., et al. Oncogene 29(16):2393-2403(2010). Nat. Genet. 41(7):824-828(2009). Jian, X., et al. J. Biol. Chem. 284(3):1652-1663(2009). Inoue, H., et al. Mol. Biol. Cell 19(10):4224-4237(2008). Lin, D., et al. Cancer Res. 68(11):4352-4359(2008).

Other Notes

Small volumes of anti-ASAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASAP1 purchase

MBS6275495 is an antibody targeting ASAP1. Also known as ASAP1, ID (ASAP1, DDEF1, KIAA1249, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130kD phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
NCBI Official Symbol
ASAP1
NCBI Official Synonym Symbols
PAP; PAG2; AMAP1; DDEF1; ZG14P; CENTB4
UniProt Protein Name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
UniProt Synonym Protein Names
130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; ARF GTPase-activating protein 1; Development and differentiation-enhancing factor 1; DEF-1; Differentiation-enhancing factor 1; PIP2-dependent ARF1 GAP
UniProt Gene Name
ASAP1
UniProt Synonym Gene Names
DDEF1; KIAA1249; ARF GTPase-activating protein 1; DEF-1
UniProt Entry Name
ASAP1_HUMAN
NCBI Protein Information
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; DEF-1; centaurin, beta 4; PIP2-dependent ARF1 GAP; ARF GTPase-activating protein 1; development and differentiation-enhancing factor 1; ADP-ribosylation factor-directed GTPase-activat

NCBI Summary for ASAP1

This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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