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CD209B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3223790

Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD209B, Polyclonal Antibody
Full Product Name
CD209B Antibody - middle region
Product Gene Name
anti-CD209B antibody
Product Synonym Gene Name
OtB7; SIGNR1; mSIGNR1; DC-SIGNR1; 1810030I22Rik
Immunogen Sequence
Synthetic peptide located within the following region: DLKKEATWLW VDGSTLSSRF QKYWNRGEPN NIGEEDCVEF AGDGWNDSKC
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CD209B peptide (MBS3248375) is used for blocking the activity of CD209B antibody (MBS3223790)
Molecular Weight
37 kDa
3D Structure
ModBase 3D Structure for Q8CJ91
Immunogen
The immunogen is a synthetic peptide directed towards the middle terminal region of mouse CD209B

Product Categories/Family for anti-CD209B antibody

Polyclonal; Immunology
Applications Tested/Suitable for anti-CD209B antibody
Western Blot (WB)

Western Blot (WB) of anti-CD209B antibody

Host: Rabbit
Target Name: CD209B
Sample Tissue: Mouse Testis lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-CD209B Polyclonal Antibody – Cat# MBS3223790

Other Notes

Small volumes of anti-CD209B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD209B purchase

MBS3223790 is an antibody targeting CD209B. Also known as CD209B Antibody - middle region. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD209B. It may not necessarily be applicable to this product.

NCBI GI #
564112202
NCBI GeneID
69165
NCBI Accession #
NP_001032889.3
UniProt Primary Accession #
Q8CJ91
UniProt Related Accession #
Q8CJ91
GenBank Nucleotide #
NM_001037800.3
NCBI Official Full Name
CD209 antigen-like protein B isoform b
NCBI Official Synonym Full Names
CD209b antigen
NCBI Official Symbol
Cd209b
NCBI Official Synonym Symbols
OtB7; SIGNR1; mSIGNR1; DC-SIGNR1; 1810030I22Rik
UniProt Protein Name
CD209 antigen-like protein B
UniProt Synonym Protein Names
DC-SIGN-related protein 1; DC-SIGNR1; OtB7; CD_antigen: CD209
Protein Family
CD209 antigen-like protein
UniProt Gene Name
Cd209b
UniProt Synonym Gene Names
DC-SIGNR1
UniProt Entry Name
C209B_MOUSE
NCBI Protein Information
CD209 antigen-like protein B

UniProt Comments for CD209B

CD209B: Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane; external side of plasma membrane

Molecular Function: mannose binding; metal ion binding; zymosan binding; carbohydrate binding; polysaccharide binding

Biological Process: positive regulation of tumor necrosis factor biosynthetic process; detection of bacterium; positive regulation of phagocytosis; endocytosis; phagocytosis, recognition; detection of yeast
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Research Articles on CD209B

1. Data suggest that SIGNR1(CD209b) expressed in Lewis lung cancer cell-educated macrophages appears to mediate IL-4-induced RAW264.7 macrophage polarization and thus facilitate lung cancer evasion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD209B antibody

 Reference Product  PubMed Publications
 Tlr4 antibody  >1 publications with CD209B and Tlr4

Pathways associated with anti-CD209B antibody

 Products by Pathway  Pathway Diagram
 C-type Lectin Receptors (CLRs) Pathway antibodies  C-type Lectin Receptors (CLRs) Pathway Diagram
 CD209 (DC-SIGN) Signaling Pathway antibodies  CD209 (DC-SIGN) Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram

Diseases associated with anti-CD209B antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with CD209B and Inflammation
 Necrosis Antibodies  >1 publications with CD209B and Necrosis

Organs/Tissues associated with anti-CD209B antibody

 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >2 publications with CD209B and Spleen
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