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CHUK Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6286041

Chuk acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Chuk, Polyclonal Antibody
Full Product Name
Chuk, CT (Chuk, Ikka, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, Nuclear factor NF-kappa-B inhibitor kinase alpha) (AP)
Product Gene Name
anti-Chuk antibody
Product Synonym Names
Chuk; Ikka; Inhibitor of nuclear factor kappa-B kinase subunit alpha; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; Nuclear factor NF-kappa-B inhibitor kinase alpha
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
84,729 Da
3D Structure
ModBase 3D Structure for Q60680
Immunogen
Mouse Chuk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 550-578 amino acids from the C-terminal region of Mouse Chuk.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-Chuk antibody

Antibodies; Protein Kinases
Applications Tested/Suitable for anti-Chuk antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-Chuk antibody
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-Chuk antibody

Mouse Chuk Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Chuk antibody detected the Chuk protein (arrow).
Rabbit Anti-CHUK Polyclonal Antibody – Cat# MBS6286041

Immunohistochemistry (IHC) of anti-Chuk antibody

Mouse Chuk Antibody (C-term) (AP14612b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Chuk Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-CHUK Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6286041

Other Notes

Small volumes of anti-Chuk antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Chuk purchase

MBS6286041 is an antibody targeting Chuk. Also known as Chuk, CT (Chuk, Ikka, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, Nuclear factor NF-kappa-B inhibitor kinase alpha) (AP). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Chuk. It may not necessarily be applicable to this product.

NCBI GI #
569006285
NCBI GeneID
12675
NCBI Accession #
XP_006526686.1
UniProt Primary Accession #
Q60680
UniProt Secondary Accession #
Q80VU2; Q9D2X3
UniProt Related Accession #
Q60680
GenBank Nucleotide #
XM_006526623.1
NCBI Official Full Name
inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
NCBI Official Synonym Full Names
conserved helix-loop-helix ubiquitous kinase
NCBI Official Symbol
Chuk
NCBI Official Synonym Symbols
IKK1; Ikka; Chuk1; Fbx24; IKBKA; Fbxo24; NFKBIKA; AI256658
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
UniProt Synonym Protein Names
Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA
Protein Family
Inhibitor of nuclear factor kappa-B kinase
UniProt Gene Name
Chuk
UniProt Synonym Gene Names
Ikka; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA
UniProt Entry Name
IKKA_MOUSE
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit alpha; IKK-A; IKK alpha; I kappa B kinase 1; I-kappa-B kinase 1; IkappaB kinase alpha; I-kappa-B kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Chuk antibody

 Reference Product  PubMed Publications
 Ikbkg antibody  >15 publications with Chuk and Ikbkg
 Nfkbia antibody  >4 publications with Chuk and Nfkbia

Pathways associated with anti-Chuk antibody

 Products by Pathway  Pathway Diagram
 AKT Phosphorylates Targets In The Cytosol Pathway antibodies  AKT Phosphorylates Targets In The Cytosol Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram

Organs/Tissues associated with anti-Chuk antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >216 publications with Chuk and Blood
 Lung Antibodies  >68 publications with Chuk and Lung
 Skin Antibodies  >62 publications with Chuk and Skin
 Bone Antibodies  >46 publications with Chuk and Bone
 Heart Antibodies  >43 publications with Chuk and Heart
 Kidney Antibodies  >35 publications with Chuk and Kidney
 Embryonic Tissue Antibodies  >34 publications with Chuk and Embryonic Tissue
 Brain Antibodies  >27 publications with Chuk and Brain
 Bone Marrow Antibodies  >26 publications with Chuk and Bone Marrow
 Intestine Antibodies  >25 publications with Chuk and Intestine
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