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DPM2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422180

MBS422180 is an antibody targeting Dpm2. Also known as Goat anti-Dpm2 (mouse) Antibody. Reactive in Expected from sequence similarity: Mouse. Host: Goat. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dpm2, Polyclonal Antibody
Full Product Name
Goat anti-Dpm2 (mouse) Antibody
Product Gene Name
anti-Dpm2 antibody
Product Synonym Names
Dpm2; dolichol-phosphate (beta-D) mannosyltransferase 2; RP23-255P20.5; AW557993; R75484; OTTMUSP00000012854; Dpm2 antibody; dolichol-phosphate (beta-D) mannosyltransferase 2 antibody; RP23-255P20.5 antibody; AW557993 antibody; R75484 antibody; OTTMUSP00000012854 antibody; Dpm2 (mouse)
Immunogen Sequence
YVMLKSQKIT KKAQ
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Mouse
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Dpm2 peptide (MBS426914) is used for blocking the activity of Dpm2 antibody (MBS422180)
Molecular Weight
9,376 Da
Immunogen
Peptide with sequence C-YVMLKSQKITKKAQ, from the C Terminus of the protein sequence according to NP_034203.1.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-Dpm2 antibody
Peptide ELISA (EIA)
Application Notes for anti-Dpm2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments gave an approx.25kDa band in Mouse Eye lysates after 0. 02ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 9.4kDa according to NP_034203.1. The 25kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-Dpm2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Dpm2. It may not necessarily be applicable to this product.

NCBI GI #
6753672
NCBI GeneID
13481
NCBI Accession #
NP_034203.1
UniProt Related Accession #
Q9Z324
GenBank Nucleotide #
NM_010073.2
NCBI Official Full Name
dolichol phosphate-mannose biosynthesis regulatory protein
NCBI Official Synonym Full Names
dolichol-phosphate (beta-D) mannosyltransferase 2
NCBI Official Symbol
Dpm2
NCBI Official Synonym Symbols
R75484; AW557993
UniProt Protein Name
Dolichol phosphate-mannose biosynthesis regulatory protein
UniProt Synonym Protein Names
Dolichol-phosphate mannose synthase subunit 2; DPM synthase subunit 2
Protein Family
Dolichol phosphate-mannose biosynthesis regulatory protein
UniProt Gene Name
Dpm2
UniProt Synonym Gene Names
DPM synthase subunit 2
UniProt Entry Name
DPM2_MOUSE
NCBI Protein Information
dolichol phosphate-mannose biosynthesis regulatory protein

UniProt Comments for Dpm2

DPM2: Regulates the biosynthesis of dolichol phosphate- mannose. Essential for the ER localization and stable expression of DPM1. Belongs to the DPM2 family.

Protein type: Transferase; Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to endoplasmic reticulum membrane; integral to membrane; membrane; perinuclear region of cytoplasm

Molecular Function: dolichyl-phosphate beta-D-mannosyltransferase activity; enzyme regulator activity; protein binding

Biological Process: dolichol metabolic process; GPI anchor biosynthetic process; protein amino acid O-linked mannosylation; regulation of catalytic activity; regulation of protein stability
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Dpm2 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies  Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-Dpm2 antibody

 Disease Name  Pubmed Publications
 Anemia Antibodies  >1 publications with Dpm2 and Anemia
 Atrophy Antibodies  >1 publications with Dpm2 and Atrophy
 Liver Diseases Antibodies  >1 publications with Dpm2 and Liver Diseases

Organs/Tissues associated with anti-Dpm2 antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >6 publications with Dpm2 and Ovary
 Liver Antibodies  >2 publications with Dpm2 and Liver
 Brain Antibodies  >2 publications with Dpm2 and Brain
 Bone Antibodies  >1 publications with Dpm2 and Bone
 Bone Marrow Antibodies  >1 publications with Dpm2 and Bone Marrow
 Eye Antibodies  >1 publications with Dpm2 and Eye
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