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DRG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6293527

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DRG2, Polyclonal Antibody
Full Product Name
DRG2, ID (DRG2, Developmentally-regulated GTP-binding protein 2) (MaxLight 490)
Product Gene Name
anti-DRG2 antibody
Product Synonym Names
DRG2; Developmentally-regulated GTP-binding protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes mouse DRG2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
40,746 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (17991283..18011292). Location: 17p11.2
OMIM
602986
3D Structure
ModBase 3D Structure for P55039
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 154-180 in the central region of human DRG2, UniProt Accession #P55039. Species sequence homology: bovine
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-DRG2 antibody

Antibodies; Binding Proteins
Applications Tested/Suitable for anti-DRG2 antibody
Western Blot (WB), FLISA
Application Notes for anti-DRG2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-DRG2 antibody

Western Blot analysis in mouse kidney tissue lysates (35ug/lane) usingMBS6001900. This demonstrates that MBS6001900 detected the DRG2 protein (arrow).
Rabbit Anti-DRG2 Polyclonal Antibody – Cat# MBS6293527

Product References and Citations for anti-DRG2 antibody

1. Song, H., et al. J. Biochem. 135(3):331-335(2004). 2. Bi, W., et al. Genome Res. 12(5):713-728(2002). 3. Li, B., et al. Biochim. Biophys. Acta 1491 (1-3), 196-204 (2000). 4. Vlangos, C.N., et al. Cytogenet. Cell Genet. 88 (3-4), 283-285 (2000). 5. Liang, Y., et al. Genomics 61(3):243-258(1999).

Other Notes

Small volumes of anti-DRG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DRG2 purchase

MBS6293527 is an antibody targeting DRG2. Also known as DRG2, ID (DRG2, Developmentally-regulated GTP-binding protein 2) (MaxLight 490). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DRG2. It may not necessarily be applicable to this product.

NCBI GI #
4557537
NCBI GeneID
1819
NCBI Accession #
NP_001379.1
UniProt Primary Accession #
P55039
UniProt Secondary Accession #
Q9BWB2; B2R8G5
UniProt Related Accession #
P55039; Q53Y50; Q59FW9
GenBank Nucleotide #
NM_001388.3
NCBI Official Full Name
developmentally-regulated GTP-binding protein 2
NCBI Official Synonym Full Names
developmentally regulated GTP binding protein 2
NCBI Official Symbol
DRG2
NCBI Official Synonym Symbols
DRG2
UniProt Protein Name
Developmentally-regulated GTP-binding protein 2
Protein Family
Dermaseptin
UniProt Gene Name
DRG2
UniProt Synonym Gene Names
DRG-2
UniProt Entry Name
DRG2_HUMAN
NCBI Protein Information
developmentally-regulated GTP-binding protein 2; DRG-2; OTTHUMP00000065704; OTTHUMP00000065705; developmentally regulated GTP-binding protein 2

NCBI Summary for DRG2

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in SV40-transformed fibroblasts. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq]
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Research Articles on DRG2

1. Basal expression level of DRG2 is regulated by the Sp1 transcription factor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DRG2 antibody

 Reference Product  PubMed Publications
 DRG1 antibody  >6 publications with DRG2 and DRG1

Diseases associated with anti-DRG2 antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >3 publications with DRG2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with DRG2 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with DRG2 and Liver Diseases
 Adenocarcinoma Antibodies  >2 publications with DRG2 and Adenocarcinoma

Organs/Tissues associated with anti-DRG2 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >5 publications with DRG2 and Embryonic Tissue
 Blood Antibodies  >4 publications with DRG2 and Blood
 Liver Antibodies  >4 publications with DRG2 and Liver
 Brain Antibodies  >3 publications with DRG2 and Brain
 Lung Antibodies  >2 publications with DRG2 and Lung
 Nerve Antibodies  >2 publications with DRG2 and Nerve
 Testis Antibodies  >1 publications with DRG2 and Testis
 Muscle Antibodies  >1 publications with DRG2 and Muscle
 Ovary Antibodies  >1 publications with DRG2 and Ovary
 Heart Antibodies  >1 publications with DRG2 and Heart
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