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ECOP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6294258

Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ECOP, Polyclonal Antibody
Full Product Name
ECOP, ID (VOPP1, ECOP, GASP, Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N) (AP)
Product Gene Name
anti-ECOP antibody
Product Synonym Gene Name
VOPP1
Product Synonym Names
VOPP1; ECOP; GASP; Vesicular; overexpressed in cancer; prosurvival protein 1; EGFR-coamplified and overexpressed protein; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
17,381 Da
OMIM
611915
3D Structure
ModBase 3D Structure for Q96AW1
Immunogen
ECOP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-103 amino acids from the Central region of human ECOP.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-ECOP antibody

Antibodies; Cancer Markers
Applications Tested/Suitable for anti-ECOP antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ECOP antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ECOP antibody

ECOP Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ECOP antibody detected the ECOP protein (arrow).
Rabbit Anti-ECOP Polyclonal Antibody – Cat# MBS6294258

Product References and Citations for anti-ECOP antibody

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010). Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010). Baras, A., et al. Oncogene 28(32):2919-2924(2009). Chechlinska, M., et al. BMC Genomics 10, 261 (2009): Brem, H., et al. Mol. Med. 13 (1-2), 30-39 (2007).

Other Notes

Small volumes of anti-ECOP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ECOP purchase

MBS6294258 is an antibody targeting ECOP. Also known as ECOP, ID (VOPP1, ECOP, GASP, Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N) (AP). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ECOP. It may not necessarily be applicable to this product.

NCBI GI #
106507239
NCBI GeneID
81552
NCBI Accession #
NP_110423.3
UniProt Primary Accession #
Q96AW1
UniProt Secondary Accession #
Q6FIE3; Q8NBN8; Q96RE5; Q9H0W4; B0AZU1; B2RAT4; B3KS72; C9JWR3
UniProt Related Accession #
Q96AW1
GenBank Nucleotide #
NM_030796.3
NCBI Official Full Name
vesicular, overexpressed in cancer, prosurvival protein 1 isoform 1
NCBI Official Synonym Full Names
vesicular, overexpressed in cancer, prosurvival protein 1
NCBI Official Symbol
VOPP1
NCBI Official Synonym Symbols
ECOP; GASP
UniProt Protein Name
Vesicular, overexpressed in cancer, prosurvival protein 1
UniProt Synonym Protein Names
EGFR-coamplified and overexpressed protein; ECop; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N
Protein Family
Vesicular, overexpressed in cancer, prosurvival protein
UniProt Gene Name
VOPP1
UniProt Synonym Gene Names
ECOP; GASP; ECop
UniProt Entry Name
VOPP1_HUMAN
NCBI Protein Information
vesicular, overexpressed in cancer, prosurvival protein 1; hypothetical protein DKFZp564K0822; Glioblastoma-amplified secreted protein; EGFR-coamplified and overexpressed protein; putative NF-kappa-B-activating protein 055N

UniProt Comments for ECOP

ECOP: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Belongs to the VOPP1/ECOP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 7p11.2

Cellular Component: cytoplasmic vesicle membrane; endosome

Molecular Function: signal transducer activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ECOP antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >4 publications with ECOP and Carcinoma
 Adenocarcinoma Antibodies  >3 publications with ECOP and Adenocarcinoma
 Carcinoma, Squamous Cell Antibodies  >3 publications with ECOP and Carcinoma, Squamous Cell
 Neoplasms, Experimental Antibodies  >1 publications with ECOP and Neoplasms, Experimental
 Lymphoma Antibodies  >1 publications with ECOP and Lymphoma

Organs/Tissues associated with anti-ECOP antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with ECOP and Brain
 Nerve Antibodies  >1 publications with ECOP and Nerve
 Esophagus Antibodies  >1 publications with ECOP and Esophagus
 Vascular Antibodies  >1 publications with ECOP and Vascular
 Stomach Antibodies  >1 publications with ECOP and Stomach
 Kidney Antibodies  >1 publications with ECOP and Kidney
 Skin Antibodies  >1 publications with ECOP and Skin
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