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FGD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6298916

FGD2 activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate,… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGD2, Polyclonal Antibody
Full Product Name
FGD2, CT (FGD2, ZFYVE4, FYVE, RhoGEF and PH domain-containing protein 2, Zinc finger FYVE domain-containing protein 4) (Azide free) (HRP)
Product Gene Name
anti-FGD2 antibody
Product Synonym Names
FGD2; ZFYVE4; FYVE; RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
74,892 Da
OMIM
605091
3D Structure
ModBase 3D Structure for Q7Z6J4
Immunogen
FGD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-537 amino acids from the C-terminal region of human FGD2.
Conjugate
HRP
Note
Preservative Free

Product Categories/Family for anti-FGD2 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger
Applications Tested/Suitable for anti-FGD2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-FGD2 antibody
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FGD2 antibody

FGD2 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the FGD2 antibody detected the FGD2 protein (arrow).
Rabbit Anti-FGD2 Polyclonal Antibody – Cat# MBS6298916

Immunohistochemistry (IHC) of anti-FGD2 antibody

FGD2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FGD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-FGD2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6298916

Product References and Citations for anti-FGD2 antibody

Huber, C., et al. J. Biol. Chem. 283(49):34002-34012(2008). Delague, V., et al. Am. J. Hum. Genet. 81(1):1-16(2007). Mungall, A.J., et al. Nature 425(6960):805-811(2003). Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003): Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002).

Other Notes

Small volumes of anti-FGD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGD2 purchase

MBS6298916 is an antibody targeting FGD2. Also known as FGD2, CT (FGD2, ZFYVE4, FYVE, RhoGEF and PH domain-containing protein 2, Zinc finger FYVE domain-containing protein 4) (Azide free) (HRP). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGD2. It may not necessarily be applicable to this product.

NCBI GI #
189217917
NCBI GeneID
221472
NCBI Accession #
NP_775829.2
UniProt Primary Accession #
Q7Z6J4
UniProt Secondary Accession #
Q5T8I1; Q6P6A8; Q6ZNL5; Q8IZ32; Q8N868; Q9H7M2
UniProt Related Accession #
Q7Z6J4
GenBank Nucleotide #
NM_173558.3
NCBI Official Full Name
FYVE, RhoGEF and PH domain-containing protein 2
NCBI Official Synonym Full Names
FYVE, RhoGEF and PH domain containing 2
NCBI Official Symbol
FGD2
NCBI Official Synonym Symbols
ZFYVE4
UniProt Protein Name
FYVE, RhoGEF and PH domain-containing protein 2
UniProt Synonym Protein Names
Zinc finger FYVE domain-containing protein 4
Protein Family
F420-dependent glucose-6-phosphate dehydrogenase
UniProt Gene Name
FGD2
UniProt Synonym Gene Names
ZFYVE4
UniProt Entry Name
FGD2_HUMAN
NCBI Protein Information
FYVE, RhoGEF and PH domain-containing protein 2; FLJ00276 protein; FGD1 family, member 2; zinc finger FYVE domain-containing protein 4

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-FGD2 antibody

 Products by Pathway  Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 P75 NTR Receptor-mediated Signalling Pathway antibodies  P75 NTR Receptor-mediated Signalling Pathway Diagram

Diseases associated with anti-FGD2 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >2 publications with FGD2 and Congenital Abnormalities
 Colitis Antibodies  >1 publications with FGD2 and Colitis
 Inflammation Antibodies  >1 publications with FGD2 and Inflammation

Organs/Tissues associated with anti-FGD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with FGD2 and Blood
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