Rabbit Anti-HMGN3 Polyclonal Antibody – Cat# MBS9132532

Western blot analysis of extracts of mouse kidney, using HMGN3 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

HMGN3 Antibody – Rabbit Polyclonal

Name: HMGN3 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9132532
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9132532

The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HMGN3, Polyclonal Antibody

Full Product Name

HMGN3 Polyclonal Antibody

Product Gene Name

anti-HMGN3 antibody

Product Synonym Names

PNAS-24; PNAS-25; TRIP7

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Purity/Purification

Affinity Purification

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

Molecular Weight

11kDa

OMIM

L40357 mRNA

3D Structure

ModBase 3D Structure for Q15651

Immunogen

Recombinant protein of human HMGN3

Storage Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Product Categories/Family for anti-HMGN3 antibody

Primary antibody

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-HMGN3 antibody

Western Blot (WB)

Application Notes for anti-HMGN3 antibody

WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-HMGN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMGN3 purchase

MBS9132532 is an antibody targeting HMGN3. Also known as HMGN3 Polyclonal Antibody. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HMGN3. It may not necessarily be applicable to this product.

NCBI GI #

23831169

NCBI GeneID

9324

NCBI Accession #

Q15651.2

UniProt Primary Accession #

Q15651

UniProt Secondary Accession #

Q5HYD3; Q7RTT0; Q969M5; Q9BZT7; B2RD37

UniProt Related Accession #

Q15651

NCBI Official Full Name

High mobility group nucleosome-binding domain-containing protein 3

NCBI Official Synonym Full Names

high mobility group nucleosomal binding domain 3

NCBI Official Symbol

HMGN3

NCBI Official Synonym Symbols

TRIP7; PNAS-24; PNAS-25

UniProt Protein Name

High mobility group nucleosome-binding domain-containing protein 3

UniProt Synonym Protein Names

Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP-7

Protein Family

High mobility group nucleosome-binding domain-containing protein

UniProt Gene Name

HMGN3

UniProt Synonym Gene Names

TRIP7; TR-interacting protein 7; TRIP-7

NCBI Protein Information

high mobility group nucleosome-binding domain-containing protein 3

UniProt Comments for HMGN3

HMGN3: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function. Belongs to the HMGN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: cytosol; nucleoplasm

Research Articles on HMGN3

1. The SNPs in the region of HMGN3 gene formed a tightly combined haplotype block in both Chinese and Caucasians. The results suggest that the genomic region containing HMGN3 gene may be associated with spine BS in Chinese.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-HMGN3 antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>1 publications with HMGN3 and Carcinoma
Adenocarcinoma Antibodies	>1 publications with HMGN3 and Adenocarcinoma
Liver Neoplasms Antibodies	>1 publications with HMGN3 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with HMGN3 and Carcinoma, Hepatocellular
Disease Models, Animal Antibodies	>1 publications with HMGN3 and Disease Models, Animal
Liver Diseases Antibodies	>1 publications with HMGN3 and Liver Diseases

Organs/Tissues associated with anti-HMGN3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with HMGN3 and Brain
Blood Antibodies	>2 publications with HMGN3 and Blood
Eye Antibodies	>2 publications with HMGN3 and Eye
Pancreas Antibodies	>2 publications with HMGN3 and Pancreas
Thyroid Antibodies	>2 publications with HMGN3 and Thyroid
Muscle Antibodies	>1 publications with HMGN3 and Muscle
Liver Antibodies	>1 publications with HMGN3 and Liver
Ovary Antibodies	>1 publications with HMGN3 and Ovary
Uterus Antibodies	>1 publications with HMGN3 and Uterus
Skin Antibodies	>1 publications with HMGN3 and Skin