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Interleukin 18 (IL18) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2120862
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MBS2120862 is an antibody targeting IL18. Also known as Cy3-Linked Polyclonal Antibody to Interleukin 18 (IL18). Reactive in Mouse. Host: Rabbit. More details

$310 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 18 (IL18), Polyclonal Antibody
Full Product Name
Cy3-Linked Polyclonal Antibody to Interleukin 18 (IL18)
Product Gene Name
anti-IL18 antibody
Product Synonym Names
IGIF; IL-1g; IL1F4; IL1-F4; Interferon-Gamma-Inducing Factor; Interleukin-1 Family Member 4; Iboctadekin; Interleukin-1 Gamma
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IL18. It has been selected for its ability to recognize IL18 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IL18 (MBS2111756)
Cy3 Conjugated Antibody: IL18 (MBS2120862)
Molecular Weight
22,135 Da
3D Structure
ModBase 3D Structure for P70380
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Cross Reactivity
Mouse
Conjugation
Cy3

Product Categories/Family for anti-IL18 antibody

Cytokine; Infection Immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL18 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-IL18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product.

NCBI GI #
6680413
NCBI GeneID
16173
NCBI Accession #
NP_032386.1
UniProt Primary Accession #
P70380
UniProt Related Accession #
P70380
GenBank Nucleotide #
NM_008360.1
NCBI Official Full Name
interleukin-18
NCBI Official Synonym Full Names
interleukin 18
NCBI Official Symbol
Il18
NCBI Official Synonym Symbols
Igif; Il-18
UniProt Protein Name
Interleukin-18
UniProt Synonym Protein Names
Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
Protein Family
Interleukin
UniProt Gene Name
Il18
UniProt Synonym Gene Names
Igif; IL-18; IFN-gamma-inducing factor; IL-1 gamma
UniProt Entry Name
IL18_MOUSE
NCBI Protein Information
interleukin-18

UniProt Comments for IL18

IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.

Protein type: Cytokine

Cellular Component: apical plasma membrane; cytoplasm; extracellular space

Molecular Function: cytokine activity

Biological Process: activation of protein kinase B; angiogenesis; cholesterol homeostasis; detection of mechanical stimulus involved in sensory perception of pain; immune response; induction of apoptosis via death domain receptors; inflammatory response; interferon-gamma biosynthetic process; interleukin-13 biosynthetic process; lipopolysaccharide-mediated signaling pathway; MAPKKK cascade; natural killer cell activation; negative regulation of myoblast differentiation; negative regulation of neutrophil apoptosis; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of activated T cell proliferation; positive regulation of apoptosis; positive regulation of chemokine production; positive regulation of collagen biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; positive regulation of interleukin-8 production; positive regulation of natural killer cell proliferation; positive regulation of neuron apoptosis; positive regulation of NF-kappaB import into nucleus; positive regulation of NK T cell proliferation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of superoxide release; positive regulation of T-helper 2 cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tumor necrosis factor production; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of vascular permeability; regulation of cell adhesion; response to hypoxia; sleep; T-helper 1 type immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL18 antibody

 Reference Product  PubMed Publications
 Casp1 antibody  >658 publications with IL18 and Casp1
 Il18r1 antibody  >235 publications with IL18 and Il18r1
 Il1b antibody  >89 publications with IL18 and Il1b
 Il18rap antibody  >44 publications with IL18 and Il18rap
 Cd69 antibody  >28 publications with IL18 and Cd69
 Stat3 antibody  >25 publications with IL18 and Stat3
 Il18bp antibody  >21 publications with IL18 and Il18bp
 Rela antibody  >13 publications with IL18 and Rela
 Nfkb1 antibody  >6 publications with IL18 and Nfkb1

Pathways associated with anti-IL18 antibody

 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram

Diseases associated with anti-IL18 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1395 publications with IL18 and Inflammation
 Necrosis Antibodies  >869 publications with IL18 and Necrosis
 Cardiovascular Diseases Antibodies  >501 publications with IL18 and Cardiovascular Diseases
 Lung Diseases Antibodies  >368 publications with IL18 and Lung Diseases
 Kidney Diseases Antibodies  >366 publications with IL18 and Kidney Diseases
 Hypersensitivity Antibodies  >293 publications with IL18 and Hypersensitivity
 Heart Diseases Antibodies  >242 publications with IL18 and Heart Diseases
 Arthritis, Rheumatoid Antibodies  >234 publications with IL18 and Arthritis, Rheumatoid
 Hypersensitivity, Immediate Antibodies  >207 publications with IL18 and Hypersensitivity, Immediate
 Atherosclerosis Antibodies  >175 publications with IL18 and Atherosclerosis

Organs/Tissues associated with anti-IL18 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >456 publications with IL18 and Liver
 Spleen Antibodies  >297 publications with IL18 and Spleen
 Brain Antibodies  >247 publications with IL18 and Brain
 Skin Antibodies  >239 publications with IL18 and Skin
 Intestine Antibodies  >192 publications with IL18 and Intestine
 Eye Antibodies  >54 publications with IL18 and Eye
 Stomach Antibodies  >43 publications with IL18 and Stomach
 Embryonic Tissue Antibodies  >39 publications with IL18 and Embryonic Tissue
 Thymus Antibodies  >30 publications with IL18 and Thymus
 Ovary Antibodies  >29 publications with IL18 and Ovary
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