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Interleukin 2 Receptor Alpha (IL2Ra) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2109077
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MBS2109077 is an antibody targeting IL2Ra. Also known as FITC-Linked Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra). Reactive in Mouse. Host: Rabbit. More details

$275 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 2 Receptor Alpha (IL2Ra), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra)
Product Gene Name
anti-IL2Ra antibody
Immunogen Sequence
Glu22~Tyr2 35
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
500ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IL2Ra. It has been selected for its ability to recognize IL2Ra in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IL2Ra (MBS2014227)
FITC Conjugated Antibody: IL2Ra (MBS2109077)
Matching Pairs
FITC Conjugated Antibody: IL2Ra (MBS2109077)
Immunogen: IL2Ra (MBS2018733)
3D Structure
ModBase 3D Structure for P01590
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
FITC
Cross Reactivity
Mouse

Product Categories/Family for anti-IL2Ra antibody

Signal transduction; CD & Adhesion molecule; Tumor immunity; Infection immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL2Ra antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-IL2Ra antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL2Ra. It may not necessarily be applicable to this product.

NCBI GI #
124318
NCBI GeneID
16184
NCBI Accession #
P01590.1
UniProt Primary Accession #
P01590
UniProt Related Accession #
P01590
NCBI Official Full Name
Interleukin-2 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 2 receptor, alpha chain
NCBI Official Symbol
Il2ra
NCBI Official Synonym Symbols
CD25; Il2r; Ly-43
UniProt Protein Name
Interleukin-2 receptor subunit alpha
UniProt Synonym Protein Names
p55; CD_antigen: CD25
Protein Family
Interleukin-2 receptor
UniProt Gene Name
Il2ra
UniProt Synonym Gene Names
Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA
UniProt Entry Name
IL2RA_MOUSE
NCBI Protein Information
interleukin-2 receptor subunit alpha

UniProt Comments for IL2Ra

IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; interleukin-2 receptor activity; drug binding; interleukin-2 binding

Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; inflammatory response to antigenic stimulus; negative regulation of T cell proliferation; positive regulation of T cell differentiation; negative regulation of inflammatory response; T cell homeostasis; positive regulation of T cell proliferation; immune response; activated T cell apoptosis
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Research Articles on IL2Ra

1. Each mutation decreased STAT5 binding and altered IL-2-induced Il2ra gene expression, revealing that individual elements within the superenhancer were not functionally redundant and that all were required for normal gene expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL2Ra antibody

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IL-2 Signaling Pathway antibodies  IL-2 Signaling Pathway Diagram

Diseases associated with anti-IL2Ra antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >522 publications with IL2Ra and Inflammation
 Necrosis Antibodies  >338 publications with IL2Ra and Necrosis
 Lung Diseases Antibodies  >194 publications with IL2Ra and Lung Diseases
 Liver Diseases Antibodies  >156 publications with IL2Ra and Liver Diseases
 Diabetes Mellitus, Type 1 Antibodies  >146 publications with IL2Ra and Diabetes Mellitus, Type 1
 Multiple Sclerosis Antibodies  >132 publications with IL2Ra and Multiple Sclerosis
 Cardiovascular Diseases Antibodies  >126 publications with IL2Ra and Cardiovascular Diseases
 Arthritis, Rheumatoid Antibodies  >114 publications with IL2Ra and Arthritis, Rheumatoid
 Kidney Diseases Antibodies  >89 publications with IL2Ra and Kidney Diseases
 HIV Infections Antibodies  >83 publications with IL2Ra and HIV Infections

Organs/Tissues associated with anti-IL2Ra antibody

 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >387 publications with IL2Ra and Spleen
 Lymph Node Antibodies  >306 publications with IL2Ra and Lymph Node
 Skin Antibodies  >216 publications with IL2Ra and Skin
 Thymus Antibodies  >206 publications with IL2Ra and Thymus
 Ovary Antibodies  >13 publications with IL2Ra and Ovary
 Mammary Gland Antibodies  >2 publications with IL2Ra and Mammary Gland
 Uncharacterized Tissue Antibodies  >1 publications with IL2Ra and Uncharacterized Tissue
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