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KLK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6404519

KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
KLK1, Polyclonal Antibody
Full Product Name
KLK1 (m.KLK1, Klk-6, Klk6, mGK-6, Glandular kallikrein K1, KAL-B, KLKR, Renal kallikrein, Tissue kallikrein-6) (MaxLight 550)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight550.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes mouse m.KLK1. No crossreactivity with other proteins.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
28,775 Da
3D Structure
ModBase 3D Structure for P15947
Immunogen
E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-KLK1 antibody

Applications Tested/Suitable for anti-KLK1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-KLK1 antibody
Applications are based on unconjugated antibody.

Product References and Citations for anti-KLK1 antibody

1. Azizi, M., Boutouyrie, P., Bissery, A., Agharazii, M., Verbeke, F., Stern, N., Bura-Riviere, A., Laurent, S., Alhenc-Gelas, F., Jeunemaitre, X. Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans. J. Clin. Invest. 115: 780-787, 2005. 2. Baker, A. R., Shine, J. Human kidney kallikrein: cDNA cloning and sequence analysis. DNA 4: 445-450, 1985. 3. Clements J, Hooper J, Dong Y, Harvey T (2001). "The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions".

Other Notes

Small volumes of anti-KLK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLK1 purchase

MBS6404519 is an antibody targeting KLK1. Also known as KLK1 (m.KLK1, Klk-6, Klk6, mGK-6, Glandular kallikrein K1, KAL-B, KLKR, Renal kallikrein, Tissue kallikrein-6) (MaxLight 550). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Kallikrein-1
NCBI Official Synonym Full Names
kallikrein 1
NCBI Official Symbol
Klk1
NCBI Official Synonym Symbols
Kal; Klk6; mGk-6; Klk1b6; 0610007D04Rik
UniProt Protein Name
Kallikrein-1
UniProt Synonym Protein Names
Glandular kallikrein K1; KAL-B; Renal kallikrein; Tissue kallikrein-6; mGK-6
Protein Family
UniProt Gene Name
Klk1
UniProt Synonym Gene Names
Klk-6; Klk6; mGK-6
UniProt Entry Name
KLK1_MOUSE
NCBI Protein Information
kallikrein-1; KAL-B; kallikrein 6; renal kallikrein; tissue kallikrein-6; true tissue kallikrein; glandular kallikrein K1; kallikrein renal/pancreas/salivary

UniProt Comments for KLK1

KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.35; Protease

Cellular Component: nucleus

Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity

Biological Process: proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLK1 antibody

 Reference Product  PubMed Publications
 Bdkrb2 antibody  >8 publications with KLK1 and Bdkrb2
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