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Platelet Derived Growth Factor D (PDGFD) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2142787
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MBS2142787 is an antibody targeting PDGFD. Also known as FITC-Linked Polyclonal Antibody to Platelet Derived Growth Factor D (PDGFD). Reactive in Mouse. Host: Rabbit. More details

$275 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Platelet Derived Growth Factor D (PDGFD), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Platelet Derived Growth Factor D (PDGFD)
Product Gene Name
anti-PDGFD antibody
Product Synonym Names
Platelet Derived Growth Factor D; PDGF-D; IEGF; SCDGF-B; Spinal Cord Derived Growth Factor B; Iris-expressed growth factor; Platelet-derived growth factor D, receptor-binding form/latent form
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=0.5mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Antibody: PDGFD (MBS2142787)
Immunogen: PDGFD (MBS2140211)
Matching Pairs
Unconjugated Antibody: PDGFD (MBS2152263)
FITC Conjugated Antibody: PDGFD (MBS2142787)
Molecular Weight
42,809 Da
Immunogen Sequence Positions
Thr24~Arg364
3D Structure
ModBase 3D Structure for Q925I7
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
FITC

Product Categories/Family for anti-PDGFD antibody

Polyclonal Antibodies (Primary Abs); Primary, FITC-conjugated; Cytokine
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PDGFD antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-PDGFD antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-PDGFD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDGFD. It may not necessarily be applicable to this product.

NCBI GI #
27229137
NCBI GeneID
71785
NCBI Accession #
NP_082200.1
UniProt Primary Accession #
Q925I7
UniProt Secondary Accession #
Q3URF6; Q8K2L3; Q9D1L8
UniProt Related Accession #
Q925I7
GenBank Nucleotide #
NM_027924.2
NCBI Official Full Name
platelet-derived growth factor D
NCBI Official Synonym Full Names
platelet-derived growth factor, D polypeptide
NCBI Official Symbol
Pdgfd
NCBI Official Synonym Symbols
1110003I09Rik
UniProt Protein Name
Platelet-derived growth factor D
UniProt Synonym Protein Names
Spinal cord-derived growth factor B; SCDGF-B
Protein Family
Platelet-derived growth factor
UniProt Gene Name
Pdgfd
UniProt Synonym Gene Names
Scdgfb; PDGF-D; SCDGF-B; PDGFD latent form; PDGFD receptor-binding form
UniProt Entry Name
PDGFD_MOUSE
NCBI Protein Information
platelet-derived growth factor D; PDGF-D; SCDGF-B; spinal cord-derived growth factor B

UniProt Comments for PDGFD

PDGFD: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Oncoprotein

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: growth factor activity; platelet-derived growth factor receptor binding

Biological Process: multicellular organismal development; positive regulation of cell division; platelet-derived growth factor receptor signaling pathway; cellular process; regulation of peptidyl-tyrosine phosphorylation
Show more

Research Articles on PDGFD

1. PDGF D represents a potentially promising target for prostate carcinoma treatment resistance in the absence of PTEN function, and warrants further laboratory evaluation and clinical study.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PDGFD antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram

Diseases associated with anti-PDGFD antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >9 publications with PDGFD and Kidney Diseases
 Fibrosis Antibodies  >9 publications with PDGFD and Fibrosis
 Inflammation Antibodies  >3 publications with PDGFD and Inflammation
 Coronary Artery Disease Antibodies  >3 publications with PDGFD and Coronary Artery Disease
 Cell Transformation, Neoplastic Antibodies  >2 publications with PDGFD and Cell Transformation, Neoplastic
 Kidney Neoplasms Antibodies  >2 publications with PDGFD and Kidney Neoplasms
 Liver Cirrhosis Antibodies  >2 publications with PDGFD and Liver Cirrhosis
 Liver Diseases Antibodies  >2 publications with PDGFD and Liver Diseases
 Hemorrhage Antibodies  >2 publications with PDGFD and Hemorrhage
 Liver Failure Antibodies  >1 publications with PDGFD and Liver Failure

Organs/Tissues associated with anti-PDGFD antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >12 publications with PDGFD and Kidney
 Prostate Antibodies  >9 publications with PDGFD and Prostate
 Brain Antibodies  >6 publications with PDGFD and Brain
 Lung Antibodies  >4 publications with PDGFD and Lung
 Eye Antibodies  >4 publications with PDGFD and Eye
 Embryonic Tissue Antibodies  >3 publications with PDGFD and Embryonic Tissue
 Connective Tissue Antibodies  >2 publications with PDGFD and Connective Tissue
 Bladder Antibodies  >1 publications with PDGFD and Bladder
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