Rabbit Anti-TBCC Polyclonal Antibody – Cat# MBS6354009

TBCC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the TBCC antibody detected the TBCC protein (arrow).

TBCC Antibody – Rabbit Polyclonal

Name: TBCC Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6354009
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6354009

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TBCC, Polyclonal Antibody

Full Product Name

TBCC, NT (TBCC, Tubulin-specific chaperone C, Tubulin-folding cofactor C) (Biotin)

Product Gene Name

anti-TBCC antibody

Product Synonym Names

TBCC; Tubulin-specific chaperone C; Tubulin-folding cofactor C

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

39,248 Da

OMIM

602971

3D Structure

ModBase 3D Structure for Q15814

Immunogen

TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human TBCC.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-TBCC antibody

Antibodies; Tubulin

Applications Tested/Suitable for anti-TBCC antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-TBCC antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-TBCC antibody

Hage-Sleiman, R., et al. BMC Cancer 10, 135 (2010): Nature 447(7145):661-678(2007). Mungall, A.J., et al. Nature 425(6960):805-811(2003). Bartolini, F., et al. J. Biol. Chem. 277(17):14629-14634(2002). Tian, G., et al. Cell 86(2):287-296(1996).

Other Notes

Small volumes of anti-TBCC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBCC purchase

MBS6354009 is an antibody targeting TBCC. Also known as TBCC, NT (TBCC, Tubulin-specific chaperone C, Tubulin-folding cofactor C) (Biotin). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TBCC. It may not necessarily be applicable to this product.

NCBI GI #

4507373

NCBI GeneID

6903

NCBI Accession #

NP_003183.1

UniProt Primary Accession #

Q15814

UniProt Secondary Accession #

Q53Y43; Q5T787

UniProt Related Accession #

Q15814

GenBank Nucleotide #

NM_003192.2

NCBI Official Full Name

tubulin-specific chaperone C

NCBI Official Synonym Full Names

tubulin folding cofactor C

NCBI Official Symbol

TBCC

NCBI Official Synonym Symbols

CFC

UniProt Protein Name

Tubulin-specific chaperone C

UniProt Synonym Protein Names

Tubulin-folding cofactor C; CFC

Protein Family

TBCC domain-containing protein

UniProt Gene Name

TBCC

UniProt Synonym Gene Names

CFC

UniProt Entry Name

TBCC_HUMAN

NCBI Protein Information

tubulin-specific chaperone C; tubulin-folding cofactor C

UniProt Comments for TBCC

TBCC: Tubulin-folding protein; involved in the final step of the tubulin folding pathway. Belongs to the TBCC family.

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: microtubule; cytoskeleton; cytoplasm; photoreceptor connecting cilium

Molecular Function: GTPase activity; chaperone binding

Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; cell morphogenesis; post-chaperonin tubulin folding pathway

Research Articles on TBCC

1. a testable model for TBCC N-terminal domain/tubulin recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin monomers

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TBCC antibody

Reference Product	PubMed Publications
TBCE antibody	>5 publications with TBCC and TBCE
TBCD antibody	>5 publications with TBCC and TBCD
ARL3 antibody	>1 publications with TBCC and ARL3

Pathways associated with anti-TBCC antibody

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-chaperonin Tubulin Folding Pathway antibodies	Post-chaperonin Tubulin Folding Pathway Diagram
Protein Folding Pathway antibodies	Protein Folding Pathway Diagram

Diseases associated with anti-TBCC antibody

Disease Name	Pubmed Publications
Neurobehavioral Manifestations Antibodies	>1 publications with TBCC and Neurobehavioral Manifestations

Organs/Tissues associated with anti-TBCC antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>11 publications with TBCC and Liver
Blood Antibodies	>8 publications with TBCC and Blood
Bone Antibodies	>3 publications with TBCC and Bone
Eye Antibodies	>3 publications with TBCC and Eye
Intestine Antibodies	>3 publications with TBCC and Intestine
Muscle Antibodies	>3 publications with TBCC and Muscle
Adrenal Gland Antibodies	>1 publications with TBCC and Adrenal Gland
Connective Tissue Antibodies	>1 publications with TBCC and Connective Tissue
Lung Antibodies	>1 publications with TBCC and Lung