• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD31/Pecam1 (PECAM1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1752989

Description: Rabbit IgG polyclonal antibody for CD31/Pecam1 detection. Tested with WB, FCM, Direct ELISA in Mouse; Rat.Background: CD31 also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a protein that in human is encoded by the PECAM1… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD31/Pecam1, Polyclonal Antibody
Full Product Name
Anti-CD31/Pecam1 Antibody
Product Gene Name
anti-Pecam1 antibody
Product Synonym Names
Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam,Pecam-1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for Q08481
Immunogen
E Coli-derived mouse CD31/Pecam1 recombinant protein (Position: Q41-E258).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-Pecam1 antibody
Western Blot (WB), Flow Cytometry (FC/FACS), Direct ELISA (EIA)
Application Notes for anti-Pecam1 antibody
WB: 0.1-0.25ug/ml (Mouse, Rat)
FC/FACS: 1-3ug/1x106 cells (Mouse)
Direct ELISA: 0.1-0.5ug/ml (Mouse)
Tested Species: In-house tested species with positive results.

Flow Cytometry (FC/FACS) of anti-Pecam1 antibody

Rabbit Anti-PECAM1 Polyclonal Antibody – Cat# MBS1752989

Western Blot (WB) of anti-Pecam1 antibody

Figure 1. Western blot analysis of Pecam1 using anti-Pecam1 antibody.
Rabbit Anti-PECAM1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS1752989

Product References and Citations for anti-Pecam1 antibody

1. Gumina, R. J., Kirschbaum, N. E., Rao, P. N., vanTuinen, P., Newman, P. J. The human PECAM1 gene maps to 17q23. Genomics 34: 229-232, 1996.
2. Wu, Y., Tworkoski, K., Michaud, M., Madri, J. A. Bone marrow monocyte PECAM-1 deficiency elicits increased osteoclastogenesis resulting in trabecular bone loss. J. Immun. 182: 2672-2679, 2009.
3. Xie, Y., Muller, W. A. Fluorescence in situ hybridization mapping of the mouse platelet endothelial cell adhesion molecule-1 (PECAM1) to mouse chromosome 6, region F3-G1. Genomics 37: 226-228, 1996.

Other Notes

Small volumes of anti-Pecam1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pecam1 purchase

MBS1752989 is an antibody targeting Pecam1. Also known as Anti-CD31/Pecam1 Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Pecam1. It may not necessarily be applicable to this product.

NCBI GI #
585658
NCBI GeneID
18613
NCBI Accession #
Q08481.1
UniProt Primary Accession #
Q08481
UniProt Related Accession #
Q08481
NCBI Official Full Name
Platelet endothelial cell adhesion molecule
NCBI Official Synonym Full Names
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol
Pecam1
NCBI Official Synonym Symbols
Cd31; Pecam; C85791; PECAM-1
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Synonym Protein Names
CD_antigen: CD31
Protein Family
Platelet endothelial cell adhesion molecule
UniProt Gene Name
Pecam1
UniProt Synonym Gene Names
Pecam; Pecam-1; PECAM-1
UniProt Entry Name
PECA1_MOUSE
NCBI Protein Information
platelet endothelial cell adhesion molecule

UniProt Comments for Pecam1

PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: extracellular space; cell surface; smooth muscle contractile fiber; membrane; integral to membrane; plasma membrane; intracellular; cell junction; lipid raft; external side of plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; wound healing; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of actin filament polymerization; positive regulation of leukocyte migration; diapedesis; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction
Show more

Research Articles on Pecam1

1. neonatal cytotoxic t lymphocytes significantly reduce IFN-gamma production upon CD31 signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Pecam1 antibody

 Reference Product  PubMed Publications
 Tnf antibody  >198 publications with Pecam1 and Tnf
 Kdr antibody  >83 publications with Pecam1 and Kdr
 Src antibody  >65 publications with Pecam1 and Src
 Ctnnb1 antibody  >50 publications with Pecam1 and Ctnnb1
 Cdh5 antibody  >7 publications with Pecam1 and Cdh5
 Ptprj antibody  >2 publications with Pecam1 and Ptprj
 Sphk1 antibody  >1 publications with Pecam1 and Sphk1

Pathways associated with anti-Pecam1 antibody

 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with anti-Pecam1 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >619 publications with Pecam1 and Cardiovascular Diseases
 Inflammation Antibodies  >493 publications with Pecam1 and Inflammation
 Necrosis Antibodies  >401 publications with Pecam1 and Necrosis
 Neoplasms, Experimental Antibodies  >259 publications with Pecam1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >238 publications with Pecam1 and Lung Diseases
 Heart Diseases Antibodies  >229 publications with Pecam1 and Heart Diseases
 Breast Neoplasms Antibodies  >205 publications with Pecam1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >184 publications with Pecam1 and Lung Neoplasms
 Liver Diseases Antibodies  >172 publications with Pecam1 and Liver Diseases
 Atherosclerosis Antibodies  >144 publications with Pecam1 and Atherosclerosis

Organs/Tissues associated with anti-Pecam1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2975 publications with Pecam1 and Blood
 Other Antibodies  >727 publications with Pecam1 and Other
 Muscle Antibodies  >680 publications with Pecam1 and Muscle
 Bone Antibodies  >607 publications with Pecam1 and Bone
 Embryonic Tissue Antibodies  >505 publications with Pecam1 and Embryonic Tissue
 Bone Marrow Antibodies  >433 publications with Pecam1 and Bone Marrow
 Lung Antibodies  >426 publications with Pecam1 and Lung
 Heart Antibodies  >346 publications with Pecam1 and Heart
 Skin Antibodies  >334 publications with Pecam1 and Skin
 Brain Antibodies  >320 publications with Pecam1 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000