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GLYAT Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2573425

The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GLYAT, Polyclonal Antibody
Full Product Name
GLYAT Polyclonal Antibody
Product Gene Name
anti-GLYAT antibody
Product Synonym Names
GLYAT; ACGNAT; CAT; GAT
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
Molecular Weight
18,506 Da
OMIM
607424
3D Structure
ModBase 3D Structure for Q6IB77
Immunogen
Recombinant fusion protein of human GLYAT

Product Categories/Family for anti-GLYAT antibody

Antibodies; Primary Antibodies; Polyclonal Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GLYAT antibody
Western Blot (WB)
Application Notes for anti-GLYAT antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-GLYAT antibody

Western blot analysis of extracts of mouse liver using GLYAT Polyclonal Antibody at 1:3000 dilution.
Rabbit Anti-GLYAT Polyclonal Antibody – Cat# MBS2573425

Other Notes

Small volumes of anti-GLYAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLYAT purchase

MBS2573425 is an antibody targeting GLYAT. Also known as GLYAT Polyclonal Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLYAT. It may not necessarily be applicable to this product.

NCBI GI #
111038143
NCBI GeneID
10249
NCBI Accession #
NP_005829.3
UniProt Primary Accession #
Q6IB77
UniProt Secondary Accession #
O14833; Q96QK7
UniProt Related Accession #
Q6IB77
GenBank Nucleotide #
NM_005838.3
NCBI Official Full Name
glycine N-acyltransferase isoform b
NCBI Official Synonym Full Names
glycine-N-acyltransferase
NCBI Official Symbol
GLYAT
NCBI Official Synonym Symbols
CAT; GAT; ACGNAT
UniProt Protein Name
Glycine N-acyltransferase
UniProt Synonym Protein Names
Acyl-CoA:glycine N-acyltransferase; AAc; Aralkyl acyl-CoA N-acyltransferase; Aralkyl acyl-CoA:amino acid N-acyltransferase; Benzoyl-coenzyme A:glycine N-acyltransferase; Glycine N-benzoyltransferase; HRP-1(CLP)
Protein Family
Glycine N-acyltransferase
UniProt Gene Name
GLYAT
UniProt Synonym Gene Names
ACGNAT; CAT; GAT; AAc
UniProt Entry Name
GLYAT_HUMAN
NCBI Protein Information
glycine N-acyltransferase; AAc; HRP-1(CLP); acyl-CoA:glycine N-acyltransferase; aralkyl acyl-CoA N-acyltransferase; aralkyl acyl-CoA:amino acid N-acyltransferase; aralkyl-CoA N-acyltransferase; benzoyl-coenzyme A:glycine N-acyltransferase; glycine N-benzo

UniProt Comments for GLYAT

GLYAT: Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. Belongs to the glycine N-acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.13; Mitochondrial; EC 2.3.1.71; Transferase

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: glycine N-benzoyltransferase activity; glycine N-acyltransferase activity; transferase activity, transferring acyl groups

Biological Process: glycine metabolic process; acyl-CoA metabolic process; response to toxin; xenobiotic metabolic process; monocarboxylic acid metabolic process
Show more

Research Articles on GLYAT

1. SNP variations causing amino acid substitutions in the human GLYAT gene influence the kinetic properties of the enzyme.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLYAT antibody

 Reference Product  PubMed Publications
 BAAT antibody  >1 publications with GLYAT and BAAT

Pathways associated with anti-GLYAT antibody

 Products by Pathway  Pathway Diagram
 Amino Acid Conjugation Pathway antibodies  Amino Acid Conjugation Pathway Diagram
 Amino Acid Conjugation Of Benzoic Acid Pathway antibodies  Amino Acid Conjugation Of Benzoic Acid Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Conjugation Of Benzoate With Glycine Pathway antibodies  Conjugation Of Benzoate With Glycine Pathway Diagram
 Conjugation Of Carboxylic Acids Pathway antibodies  Conjugation Of Carboxylic Acids Pathway Diagram
 Conjugation Of Salicylate With Glycine Pathway antibodies  Conjugation Of Salicylate With Glycine Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram

Diseases associated with anti-GLYAT antibody

 Disease Name  Pubmed Publications
 Kidney Neoplasms Antibodies  >2 publications with GLYAT and Kidney Neoplasms
 Liver Neoplasms Antibodies  >2 publications with GLYAT and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with GLYAT and Liver Diseases
 Carcinoma Antibodies  >1 publications with GLYAT and Carcinoma
 Adenocarcinoma Antibodies  >1 publications with GLYAT and Adenocarcinoma
 Hepatitis Antibodies  >1 publications with GLYAT and Hepatitis
 Inflammation Antibodies  >1 publications with GLYAT and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with GLYAT and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with GLYAT and Kidney Diseases

Organs/Tissues associated with anti-GLYAT antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with GLYAT and Liver
 Kidney Antibodies  >3 publications with GLYAT and Kidney
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