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MAP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9142757

Background: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat… More details

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Product Overview

Online Datasheet in PDF
Product Name
Map2, Polyclonal Antibody
Full Product Name
Map2 Rabbit pAb
Product Gene Name
anti-Map2 antibody
Product Synonym Names
MAP2; MAP2A; MAP2B; MAP2C; Map2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
199,526 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (210288771..210598834). Location: 2q34-q35
OMIM
157130
3D Structure
ModBase 3D Structure for P11137
Immunogen
Recombinant protein of human Map2.
Cellular Location
Cytoplasm, cytoskeleton
Positive Samples
mouse kidney, rat testis

Product Categories/Family for anti-Map2 antibody

Cell Biology & Developmental Biology; Cytoskeleton; Microtubules; Research; Neuroscience; Cell Type Marker; Neuron marker
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-Map2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-Map2 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
Customer Validation: IF: Rat, Mouse

Western Blot (WB) of anti-Map2 antibody

Western blot analysis of extracts of various cell lines, using Map2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.
Rabbit Anti-MAP2 Polyclonal Antibody – Cat# MBS9142757

Immunohistochemistry (IHC) of anti-Map2 antibody

Immunohistochemistry of paraffin-embedded rat brain using Map2 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-MAP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9142757

Immunohistochemistry (IHC) of anti-Map2 antibody

Immunohistochemistry of paraffin-embedded mouse brain using Map2 antibody at dilution of 1:100 (40x lens).
Rabbit Anti-MAP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9142757

Immunofluorescence (IF) of anti-Map2 antibody

Immunofluorescence analysis of rat brain cells using Map2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Rabbit Anti-MAP2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS9142757

Immunofluorescence (IF) of anti-Map2 antibody

Immunofluorescence analysis of mouse brain cells using Map2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Rabbit Anti-MAP2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS9142757

Other Notes

Small volumes of anti-Map2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Map2 purchase

MBS9142757 is an antibody targeting Map2. Also known as Map2 Rabbit pAb. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Map2. It may not necessarily be applicable to this product.

NCBI GI #
87578396
NCBI GeneID
4133
NCBI Accession #
NP_002365.3
UniProt Primary Accession #
P11137
UniProt Secondary Accession #
Q17S04; Q8IUX2; Q99975; Q99976
UniProt Related Accession #
P11137
GenBank Nucleotide #
NM_002374.3
NCBI Official Full Name
microtubule-associated protein 2 isoform 1
NCBI Official Synonym Full Names
microtubule-associated protein 2
NCBI Official Symbol
MAP2
NCBI Official Synonym Symbols
MAP2A; MAP2B; MAP2C
UniProt Protein Name
Microtubule-associated protein 2
Protein Family
Microtubule-associated protein
UniProt Gene Name
MAP2
UniProt Synonym Gene Names
MAP-2
UniProt Entry Name
MTAP2_HUMAN
NCBI Protein Information
microtubule-associated protein 2; MAP-2

NCBI Summary for Map2

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
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UniProt Comments for Map2

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft

Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity

Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development
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Research Articles on Map2

1. MAP-2 and nestin participate in the regulation of the development of gastric tissues in human embryos.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Map2 antibody

 Reference Product  PubMed Publications
 MBP antibody  >25 publications with Map2 and MBP
 SRC antibody  >8 publications with Map2 and SRC
 FYN antibody  >7 publications with Map2 and FYN
 GRB2 antibody  >2 publications with Map2 and GRB2

Pathways associated with anti-Map2 antibody

 Products by Pathway  Pathway Diagram
 LKB1 Signaling Events Pathway antibodies  LKB1 Signaling Events Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram

Diseases associated with anti-Map2 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >463 publications with Map2 and Nervous System Diseases
 Brain Diseases Antibodies  >401 publications with Map2 and Brain Diseases
 Cardiovascular Diseases Antibodies  >140 publications with Map2 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >94 publications with Map2 and Drug Toxicity
 Nerve Degeneration Antibodies  >67 publications with Map2 and Nerve Degeneration
 Movement Disorders Antibodies  >37 publications with Map2 and Movement Disorders
 Necrosis Antibodies  >26 publications with Map2 and Necrosis
 Atrophy Antibodies  >25 publications with Map2 and Atrophy
 Immune System Diseases Antibodies  >24 publications with Map2 and Immune System Diseases
 Inflammation Antibodies  >23 publications with Map2 and Inflammation

Organs/Tissues associated with anti-Map2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1293 publications with Map2 and Brain
 Nerve Antibodies  >510 publications with Map2 and Nerve
 Embryonic Tissue Antibodies  >134 publications with Map2 and Embryonic Tissue
 Bone Antibodies  >58 publications with Map2 and Bone
 Eye Antibodies  >51 publications with Map2 and Eye
 Muscle Antibodies  >42 publications with Map2 and Muscle
 Vascular Antibodies  >40 publications with Map2 and Vascular
 Adrenal Gland Antibodies  >22 publications with Map2 and Adrenal Gland
 Liver Antibodies  >20 publications with Map2 and Liver
 Kidney Antibodies  >18 publications with Map2 and Kidney
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