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RACGAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2556190

Rac GTPase-activating protein 1 (RACGAP1), localized in the mitotic spindle, has guanosine triphosphatase-activating protein (GAP) activity for the Rho family GTPases. RACGAP1 has an important influence on the initiation of cytokinesis, control of cell growth… More details

$235 / 0.06 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RACGAP1, Polyclonal Antibody
Full Product Name
RACGAP1 Polyclonal Antibody
Product Gene Name
anti-RACGAP1 antibody
Product Synonym Names
CYK4; GAP; Gap1; GTPase activating protein; HsCYK-4; ID GAP; KIAA1478; Male germ cell RacGap; MgcRacGAP; Protein CYK4 homolg; Protein CYK4 homolog; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RACGAP 1; Racgap1; RGAP1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Purity/Purification
Affinity Purification
Concentration
1.7 mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
70,158 Da
3D Structure
ModBase 3D Structure for Q9WVM1
Immunogen
Recombinant protein corresponding to Mouse Racgap1
Conjugation
Unconjugated

Product Categories/Family for anti-RACGAP1 antibody

Cancer; Cell Biology; Signal transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RACGAP1 antibody
Immunohistochemistry (IHC)
Application Notes for anti-RACGAP1 antibody
IHC: 1:500-1:1000

Immunohistochemistry (IHC) of anti-RACGAP1 antibody

Immunohistochemistry analysis of paraffin-embedded mouse testis using RACGAP1 Polyclonal Antibody at dilution of 1:400.
Rabbit Anti-RACGAP1 Polyclonal Antibody – Cat# MBS2556190

Immunohistochemistry (IHC) of anti-RACGAP1 antibody

Immunohistochemistry analysis of paraffin-embedded mouse thymus using RACGAP1 Polyclonal Antibody at dilution of 1:400.
Rabbit Anti-RACGAP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2556190

Other Notes

Small volumes of anti-RACGAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RACGAP1 purchase

MBS2556190 is an antibody targeting RACGAP1. Also known as RACGAP1 Polyclonal Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RACGAP1. It may not necessarily be applicable to this product.

NCBI GI #
359385704
NCBI GeneID
26934
NCBI Accession #
NP_001240737.1
UniProt Primary Accession #
Q9WVM1
UniProt Secondary Accession #
Q3THR5; Q3TI41; Q3TM81
UniProt Related Accession #
Q9WVM1
GenBank Nucleotide #
NM_001253808.1
NCBI Official Full Name
rac GTPase-activating protein 1
NCBI Official Synonym Full Names
Rac GTPase-activating protein 1
NCBI Official Symbol
Racgap1
NCBI Official Synonym Symbols
gtl11; Band25; GTPase; AI227039; AI327394; MgcRacGAP; mKIAA1478
UniProt Protein Name
Rac GTPase-activating protein 1
UniProt Synonym Protein Names
Male germ cell RacGap; MgcRacGAP
Protein Family
Rac GTPase-activating protein
UniProt Gene Name
Racgap1
UniProt Synonym Gene Names
MgcRacGAP
NCBI Protein Information
rac GTPase-activating protein 1

UniProt Comments for RACGAP1

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.
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Research Articles on RACGAP1

1. Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RACGAP1 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Kinesins Pathway antibodies  Kinesins Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signal Transduction Of S1P Receptor Pathway antibodies  Signal Transduction Of S1P Receptor Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram

Diseases associated with anti-RACGAP1 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >4 publications with RACGAP1 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >3 publications with RACGAP1 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >3 publications with RACGAP1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with RACGAP1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >3 publications with RACGAP1 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with RACGAP1 and Liver Diseases
 Lung Neoplasms Antibodies  >3 publications with RACGAP1 and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >1 publications with RACGAP1 and Prostatic Neoplasms
 Infertility, Female Antibodies  >1 publications with RACGAP1 and Infertility, Female
 Cell Transformation, Neoplastic Antibodies  >1 publications with RACGAP1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-RACGAP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >4 publications with RACGAP1 and Lymph Node
 Liver Antibodies  >4 publications with RACGAP1 and Liver
 Lung Antibodies  >4 publications with RACGAP1 and Lung
 Brain Antibodies  >3 publications with RACGAP1 and Brain
 Testis Antibodies  >2 publications with RACGAP1 and Testis
 Bladder Antibodies  >1 publications with RACGAP1 and Bladder
 Bone Antibodies  >1 publications with RACGAP1 and Bone
 Kidney Antibodies  >1 publications with RACGAP1 and Kidney
 Heart Antibodies  >1 publications with RACGAP1 and Heart
 Intestine Antibodies  >1 publications with RACGAP1 and Intestine
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