• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RIP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9429436

MBS9429436 is an antibody targeting RIP3. Also known as RIP3 (Phospho-S232) Antibody. Reactive in Mouse, rat. Host: Rabbit. More details

$260 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RIP3, Polyclonal Antibody
Full Product Name
RIP3 (Phospho-S232) Antibody
Product Gene Name
Product Synonym Names
Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; Receptor interacting serine/threonine protein kinase 3; Receptor-interacting protein 3; Receptor-interacting serine/threonine-protein kinase 3; RIP 3; RIP like protein kinase 3; RIP-3; RIP-like protein kinase 3; RIPK 3; RIPK3; RIPK3_HUMAN;
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, rat
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Concentration
1.0mg/mL (lot specific)
Specificity
Phospho-RIP3 (Phospho- S232) Antibody detects endogenous levels of RIP3 only when phosphorylated at S232
Preparation and Storage
Store at -20 degree C.
Molecular Weight
57
3D Structure
ModBase 3D Structure for Q9QZL0
Immunogen
A synthesized peptide derived from mouse RIP3 around the phosphorylation site of Ser232
Immunogen Type
Peptide

Product Categories/Family for anti-RIP3 antibody

Applications Tested/Suitable for anti-RIP3 antibody
Western Blot (WB)
Application Notes for anti-RIP3 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-RIP3 antibody

Western blot analysis of Phospho-RIP3 (S232) in lysates of L-929, using Phospho-RIP3 (S232) Antibody(13284).
Rabbit Anti-RIP3 Polyclonal Antibody – Cat# MBS9429436

Other Notes

Small volumes of anti-RIP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RIP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 3 isoform 1
NCBI Official Synonym Full Names
receptor-interacting serine-threonine kinase 3
NCBI Official Symbol
Ripk3
NCBI Official Synonym Symbols
Rip3; AW107945; 2610528K09Rik
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 3
UniProt Synonym Protein Names
RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3; mRIP3
UniProt Gene Name
Ripk3
UniProt Synonym Gene Names
Rip3; RIP-3; mRIP3
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 3

UniProt Comments for RIP3

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000