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S1PR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2574685

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
S1PR2, Polyclonal Antibody
Full Product Name
S1PR2 Polyclonal Antibody
Product Gene Name
anti-S1PR2 antibody
Product Synonym Names
EDG5; H218; LPB2; S1P2; AGR16; EDG-5; DFNB68; Gpcr13; S1PR2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
Molecular Weight
38,867 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (10332109..10341948, complement). Location: 19p13.2
OMIM
605111
3D Structure
ModBase 3D Structure for O95136
Immunogen
A synthetic peptide of human S1PR2
Research Area
Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Product Categories/Family for anti-S1PR2 antibody

Antibodies; Primary Antibodies; Polyclonal Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-S1PR2 antibody
Western Blot (WB)
Application Notes for anti-S1PR2 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-S1PR2 antibody

Western blot analysis of Mouse heart using S1PR2 Polyclonal Antibody at 1:1000 dilution.
Rabbit Anti-S1PR2 Polyclonal Antibody – Cat# MBS2574685

Western Blot (WB) of anti-S1PR2 antibody

Western blot analysis of various lysates using S1PR2 Polyclonal Antibody at 1:1000 dilution.
Rabbit Anti-S1PR2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2574685

Other Notes

Small volumes of anti-S1PR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S1PR2 purchase

MBS2574685 is an antibody targeting S1PR2. Also known as S1PR2 Polyclonal Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for S1PR2. It may not necessarily be applicable to this product.

NCBI GI #
134244587
NCBI GeneID
9294
NCBI Accession #
NP_004221.3
UniProt Primary Accession #
O95136
UniProt Secondary Accession #
Q86UN8
UniProt Related Accession #
O95136
GenBank Nucleotide #
NM_004230.3
NCBI Official Full Name
sphingosine 1-phosphate receptor 2
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 2
NCBI Official Symbol
S1PR2
NCBI Official Synonym Symbols
EDG5; H218; LPB2; S1P2; AGR16; EDG-5; Gpcr13
UniProt Protein Name
Sphingosine 1-phosphate receptor 2
UniProt Synonym Protein Names
Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5
Protein Family
Sphingosine 1-phosphate receptor
UniProt Gene Name
S1PR2
UniProt Synonym Gene Names
EDG5; S1P receptor 2; S1P2
UniProt Entry Name
S1PR2_HUMAN
NCBI Protein Information
sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; sphingosine 1-phosphate receptor Edg-5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled recept

NCBI Summary for S1PR2

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation [provided by RefSeq, Jul 2008]

UniProt Comments for S1PR2

EDG5: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Lipid-binding; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: integrin binding; G-protein coupled receptor activity; G-protein-coupled receptor binding; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway; activation of MAPK activity; positive regulation of cell proliferation
Show more

Research Articles on S1PR2

1. Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-S1PR2 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Lysosphingolipid And LPA Receptors Pathway antibodies  Lysosphingolipid And LPA Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 S1P2 Pathway antibodies  S1P2 Pathway Diagram
 S1P3 Pathway antibodies  S1P3 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-S1PR2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with S1PR2 and Inflammation
 Immune System Diseases Antibodies  >6 publications with S1PR2 and Immune System Diseases
 Neoplasms Antibodies  >6 publications with S1PR2 and Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with S1PR2 and Cardiovascular Diseases
 Fibrosis Antibodies  >3 publications with S1PR2 and Fibrosis
 Edema Antibodies  >3 publications with S1PR2 and Edema
 Pulmonary Edema Antibodies  >2 publications with S1PR2 and Pulmonary Edema
 Kidney Diseases Antibodies  >2 publications with S1PR2 and Kidney Diseases
 Nervous System Diseases Antibodies  >2 publications with S1PR2 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with S1PR2 and Necrosis

Organs/Tissues associated with anti-S1PR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >10 publications with S1PR2 and Muscle
 Connective Tissue Antibodies  >6 publications with S1PR2 and Connective Tissue
 Lung Antibodies  >5 publications with S1PR2 and Lung
 Embryonic Tissue Antibodies  >5 publications with S1PR2 and Embryonic Tissue
 Uterus Antibodies  >3 publications with S1PR2 and Uterus
 Lymph Node Antibodies  >3 publications with S1PR2 and Lymph Node
 Lymph Antibodies  >2 publications with S1PR2 and Lymph
 Heart Antibodies  >2 publications with S1PR2 and Heart
 Ovary Antibodies  >1 publications with S1PR2 and Ovary
 Placenta Antibodies  >1 publications with S1PR2 and Placenta
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