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TRPV2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421846

MBS421846 is an antibody targeting TRPV2. Also known as Goat anti-Trpv2 (mouse) Antibody. Reactive in Tested: Rat; Expected from sequence similarity: Mouse, Rat. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Trpv2, Polyclonal Antibody
Full Product Name
Goat anti-Trpv2 (mouse) Antibody
Product Gene Name
anti-TRPV2 antibody
Product Synonym Names
Trpv2; transient receptor potential cation channel, subfamily V, member 2; RP23-234K24.7; GRC; OTRPC2; VRL-1; Vrl1; vanilloid receptor-like protein 1; Trpv2 antibody; transient receptor potential cation channel; subfamily V; member 2 antibody; RP23-234K24.7 antibody; GRC antibody; OTRPC2 antibody; VRL-1 antibody; Vrl1 antibody; vanilloid receptor-like protein 1 antibody; Trpv2 (mouse)
Immunogen Sequence
SEEDHLPLQV LQSH
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Rat; Expected from sequence similarity: Mouse, Rat
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Trpv2 peptide (MBS426338) is used for blocking the activity of Trpv2 antibody (MBS421846)
Molecular Weight
85,965 Da
Immunogen
Peptide with sequence C-SEEDHLPLQVLQSH, from the C Terminus of the protein sequence according to NP_035836.2.
Epitope
C Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-TRPV2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-TRPV2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 100kDa band observed in Rat Brain lysates (calculated MW of 86. 0kDa according to Mouse NP_035836.2 and of 86.7kDa acording to Rat NP_058903.2). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-TRPV2 antibody

(2ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-TRPV2 Polyclonal Antibody – Cat# MBS421846

Other Notes

Small volumes of anti-TRPV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRPV2. It may not necessarily be applicable to this product.

NCBI GI #
134053865
NCBI GeneID
22368
NCBI Accession #
NP_035836.2
UniProt Secondary Accession #
Q99K71
UniProt Related Accession #
Q9WTR1
GenBank Nucleotide #
NM_011706.2
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 2
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 2
NCBI Official Symbol
Trpv2
NCBI Official Synonym Symbols
GRC; Vrl1; VRL-1; OTRPC2
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 2
UniProt Synonym Protein Names
Growth factor-regulated calcium channel; GRC; Osm-9-like TRP channel 2; OTRPC2
Protein Family
Transient receptor potential cation channel subfamily
UniProt Gene Name
Trpv2
UniProt Synonym Gene Names
Grc; TrpV2; GRC; OTRPC2
UniProt Entry Name
TRPV2_MOUSE
NCBI Protein Information
transient receptor potential cation channel subfamily V member 2

UniProt Comments for TRPV2

TRPV2: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation

Cellular Component: axon; cell surface; cytoplasm; endomembrane system; integral to membrane; intracellular; lamellipodium; membrane; plasma membrane

Molecular Function: calcium channel activity; cation channel activity; ion channel activity

Biological Process: apoptosis; calcium ion transport; ion transport; negative regulation of cell proliferation; positive regulation of axon extension; response to heat; response to temperature stimulus; transmembrane transport; transport
Show more

Research Articles on TRPV2

1. TRPV2 channels play a predominant role in fluid flow mechanosensitivity over that of TRPC1 and TRP melastatin (TRPM) 7.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TRPV2 antibody

 Products by Pathway  Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 TRP Channels Pathway antibodies  TRP Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-TRPV2 antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >67 publications with TRPV2 and Pain
 Nervous System Diseases Antibodies  >37 publications with TRPV2 and Nervous System Diseases
 Inflammation Antibodies  >27 publications with TRPV2 and Inflammation
 Hyperalgesia Antibodies  >17 publications with TRPV2 and Hyperalgesia
 Disease Models, Animal Antibodies  >15 publications with TRPV2 and Disease Models, Animal
 Necrosis Antibodies  >7 publications with TRPV2 and Necrosis
 Neoplasms, Experimental Antibodies  >6 publications with TRPV2 and Neoplasms, Experimental
 Gastrointestinal Diseases Antibodies  >4 publications with TRPV2 and Gastrointestinal Diseases
 Peripheral Nervous System Diseases Antibodies  >4 publications with TRPV2 and Peripheral Nervous System Diseases
 Hypertension Antibodies  >4 publications with TRPV2 and Hypertension

Organs/Tissues associated with anti-TRPV2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >46 publications with TRPV2 and Brain
 Dorsal Root Ganglion Antibodies  >43 publications with TRPV2 and Dorsal Root Ganglion
 Skin Antibodies  >36 publications with TRPV2 and Skin
 Blood Antibodies  >34 publications with TRPV2 and Blood
 Heart Antibodies  >20 publications with TRPV2 and Heart
 Bladder Antibodies  >18 publications with TRPV2 and Bladder
 Eye Antibodies  >14 publications with TRPV2 and Eye
 Kidney Antibodies  >11 publications with TRPV2 and Kidney
 Bone Antibodies  >8 publications with TRPV2 and Bone
 Liver Antibodies  >6 publications with TRPV2 and Liver
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