• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ALDH1A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540959

Affinity Purified Aldehyde Dehydrogenase family 1 member A1 AntibodyIs capable of converting 9-cis and all-trans retinal to corresponding retinoic acid with high efficiency, 9-cis retinal being 2-fold more active than all-trans retinal. More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALDH1A1, Polyclonal Antibody
Full Product Name
ALDH1A1 Antibody
Product Gene Name
anti-ALDH1A1 antibody
Product Synonym Names
Acetaldehyde dehydrogenase 1; AHD2; ALDC; Aldehyde dehydrogenase 1 family member A1; Aldehyde dehydrogenase 1 soluble; Aldehyde dehydrogenase 1A1; Aldehyde dehydrogenase; Aldehyde dehydrogenase cytosolic; Aldehyde dehydrogenase liver cytosolic; ALDH 1; ALDH 1A1; ALDH class 1; ALDH, liver cytosolic; ALDH-E1; ALDH1; ALDH11; ALDH1A1; ALHDII; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; HEL-S-53e; MGC2318; PUMB1; RALDH 1; Retinal dehydrogenase 1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Affinity Purified
Concentration
0.5-1.5 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
ALDH1A1 peptide (MBS542347) is used for blocking the activity of ALDH1A1 antibody (MBS540959)
Matching Pairs
Antibody: ALDH1A1 (MBS540959)
Positive Control: ALDH1A1 (MBS542516)
Molecular Weight
54,459 Da
3D Structure
ModBase 3D Structure for P51647
Immunogen
Synthetic peptide taken within amino acid region 441-491 on rat retinal dehydrogenase 1 protein.
Immunoglobulin
IgG
Expression
Strongly expressed in kidney, lung, testis, intestine, stomach, and trachea, but weakly in the liver.
Molecular Function
Oxidoreductase
Structure
Belongs to the aldehyde dehydrogenase family.
Subcellular Location
Cytoplasm

Product Categories/Family for anti-ALDH1A1 antibody

Primary Antibodies; Neuroscience; Neurodegenerative Disease; Parkinson'; s Disease; ALDH1A1 Antibody
Applications Tested/Suitable for anti-ALDH1A1 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-ALDH1A1 antibody
ELISA: 1:50,000
Immunoprecipitation: 1:200
Western Blot: 1:2,500-1:5,000

Western Blot (WB) of anti-ALDH1A1 antibody

Rabbit Anti-ALDH1A1 Polyclonal Antibody – Cat# MBS540959

Other Notes

Small volumes of anti-ALDH1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1A1 purchase

MBS540959 is an antibody targeting ALDH1A1. Also known as ALDH1A1 Antibody. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1A1. It may not necessarily be applicable to this product.

NCBI GI #
14192935
NCBI GeneID
24188
NCBI Accession #
NP_071852
UniProt Primary Accession #
P51647
UniProt Secondary Accession #
O09184
UniProt Related Accession #
P51647
GenBank Nucleotide #
NM_022407.3
NCBI Official Full Name
retinal dehydrogenase 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A1
NCBI Official Symbol
Aldh1a1
NCBI Official Synonym Symbols
Ahd2; Aldh1; Aldh2
UniProt Protein Name
Retinal dehydrogenase 1
UniProt Synonym Protein Names
ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
Protein Family
Retinal dehydrogenase
UniProt Gene Name
Aldh1a1
UniProt Synonym Gene Names
Aldh; RALDH 1; RalDH1
UniProt Entry Name
AL1A1_RAT
NCBI Protein Information
retinal dehydrogenase 1

NCBI Summary for ALDH1A1

ubiquitous enzyme located in virtually all mammalian tissues; catalyzes oxidation of aldehyde substrates to carboxylic acids; detoxifies ethanol-derived acetaldehyde [RGD, Feb 2006]

UniProt Comments for ALDH1A1

ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; GAPs; EC 1.2.1.36; GAPs, Ras; Apoptosis

Cellular Component: cytoplasm; nucleus

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; benzaldehyde dehydrogenase (NAD+) activity; identical protein binding; retinal dehydrogenase activity

Biological Process: 9-cis-retinoic acid biosynthetic process; 9-cis-retinoic acid metabolic process; embryonic eye morphogenesis; kidney development; liver development; midgut development; optic cup morphogenesis involved in camera-type eye development; positive regulation of apoptosis; protein homotetramerization; response to drug; response to estradiol stimulus; response to ethanol; response to organic cyclic substance; response to oxidative stress; response to retinoic acid; retinoic acid metabolic process; retinol metabolic process
Show more

Research Articles on ALDH1A1

1. Overexpression and inhibition of ALDH1A1 activity results in reduced and increased HNE toxicity, respectively.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH1A1 antibody

 Reference Product  PubMed Publications
 Cyp26b1 antibody  >16 publications with ALDH1A1 and Cyp26b1
 Cyp26a1 antibody  >15 publications with ALDH1A1 and Cyp26a1
 Adh1c antibody  >15 publications with ALDH1A1 and Adh1c
 Adh4 antibody  >8 publications with ALDH1A1 and Adh4
 Adh5 antibody  >5 publications with ALDH1A1 and Adh5
 Adh7 antibody  >3 publications with ALDH1A1 and Adh7
 Adh6 antibody  >2 publications with ALDH1A1 and Adh6
 Acss2 antibody  >1 publications with ALDH1A1 and Acss2

Pathways associated with anti-ALDH1A1 antibody

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Fructose Catabolism Pathway antibodies  Fructose Catabolism Pathway Diagram
 Fructose Metabolism Pathway antibodies  Fructose Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram

Diseases associated with anti-ALDH1A1 antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >38 publications with ALDH1A1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >33 publications with ALDH1A1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >26 publications with ALDH1A1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >24 publications with ALDH1A1 and Nervous System Diseases
 Brain Diseases Antibodies  >23 publications with ALDH1A1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >22 publications with ALDH1A1 and Neoplasms, Experimental
 Liver Diseases Antibodies  >19 publications with ALDH1A1 and Liver Diseases
 Liver Neoplasms Antibodies  >14 publications with ALDH1A1 and Liver Neoplasms
 Parkinsonian Disorders Antibodies  >14 publications with ALDH1A1 and Parkinsonian Disorders
 Inflammation Antibodies  >11 publications with ALDH1A1 and Inflammation

Organs/Tissues associated with anti-ALDH1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >58 publications with ALDH1A1 and Lung
 Liver Antibodies  >54 publications with ALDH1A1 and Liver
 Brain Antibodies  >44 publications with ALDH1A1 and Brain
 Eye Antibodies  >33 publications with ALDH1A1 and Eye
 Colon Antibodies  >20 publications with ALDH1A1 and Colon
 Prostate Antibodies  >19 publications with ALDH1A1 and Prostate
 Muscle Antibodies  >15 publications with ALDH1A1 and Muscle
 Testis Antibodies  >15 publications with ALDH1A1 and Testis
 Kidney Antibodies  >13 publications with ALDH1A1 and Kidney
 Stomach Antibodies  >11 publications with ALDH1A1 and Stomach
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000