Rabbit Anti-C9 Polyclonal Antibody – Cat# MBS2112158

Western Blot; Sample: Recombinant C9, Rat.

Complement Component 9 (C9) Antibody – Rabbit Polyclonal

Name: C9 Antibody; Polyclonal; Rabbit; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2112158
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2112158

MBS2112158 is an antibody targeting C9. Also known as Polyclonal Antibody to Complement Component 9 (C9). Reactive in Rat. Host: Rabbit. More details

$215 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Complement Component 9 (C9), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to Complement Component 9 (C9)

Product Gene Name

anti-C9 antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Rat

Form/Format

Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Purity/Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Concentration

0.5mg/ml (lot specific)

Specificity

The antibody is a rabbit polyclonal antibody raised against C9. It has been selected for its ability to recognize C9 in immunohistochemical staining and western blotting.

Preparation and Storage

Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Matching Pairs

Unconjugated Antibody: C9 (MBS2112158)
Biotin Conjugated Antibody: C9 (MBS2113410)

Matching Pairs

Unconjugated Antibody: C9 (MBS2112158)
FITC Conjugated Antibody: C9 (MBS2114635)

Molecular Weight

62,281 Da

3D Structure

ModBase 3D Structure for Q62930

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Cross Reactivity

Rat

Conjugation

None

Product Categories/Family for anti-C9 antibody

Enzyme & Kinase; Metabolic Pathway; Infection Immunity; Immune Molecule Hematology

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-C9 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-C9 antibody

WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-C9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C9. It may not necessarily be applicable to this product.

NCBI GI #

16924006

NCBI GeneID

117512

NCBI Accession #

NP_476487.1

UniProt Primary Accession #

Q62930

UniProt Secondary Accession #

Q62957

UniProt Related Accession #

Q62930

GenBank Nucleotide #

NM_057146.1

NCBI Official Full Name

complement component C9

NCBI Official Synonym Full Names

complement component 9

NCBI Official Symbol

UniProt Protein Name

Complement component C9

Protein Family

Complement component

UniProt Gene Name

UniProt Entry Name

CO9_RAT

NCBI Protein Information

complement component C9

NCBI Summary for C9

component of the terminal complement complex C5b-9, which induces cleavage and activation of caspase 3 and mediates induction of apoptosis [RGD, Feb 2006]

UniProt Comments for C9

C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Extracellular matrix; Apoptosis; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: cytoplasm; extracellular region; membrane attack complex; plasma membrane

Biological Process: blood coagulation; complement activation, alternative pathway; complement activation, classical pathway; cytolysis; immune response

Research Articles on C9

1. The present study thus defines a novel role for ASK1 as a mediator of C5b-9-dependent cell injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-C9 antibody

Reference Product	PubMed Publications
Cd59 antibody	>156 publications with C9 and Cd59
C8g antibody	>11 publications with C9 and C8g
C8a antibody	>7 publications with C9 and C8a
C8b antibody	>6 publications with C9 and C8b
Plg antibody	>1 publications with C9 and Plg
Vtn antibody	>1 publications with C9 and Vtn

Pathways associated with anti-C9 antibody

Products by Pathway	Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Complement Activation, Classical Pathway antibodies	Complement Activation, Classical Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Prion Diseases Pathway antibodies	Prion Diseases Pathway Diagram

Diseases associated with anti-C9 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>282 publications with C9 and Immune System Diseases
Inflammation Antibodies	>148 publications with C9 and Inflammation
Cardiovascular Diseases Antibodies	>141 publications with C9 and Cardiovascular Diseases
Kidney Diseases Antibodies	>136 publications with C9 and Kidney Diseases
Necrosis Antibodies	>89 publications with C9 and Necrosis
Brain Diseases Antibodies	>82 publications with C9 and Brain Diseases
Fatty Liver Antibodies	>64 publications with C9 and Fatty Liver
Neoplasms, Experimental Antibodies	>52 publications with C9 and Neoplasms, Experimental
Liver Diseases Antibodies	>52 publications with C9 and Liver Diseases
Weight Loss Antibodies	>34 publications with C9 and Weight Loss

Organs/Tissues associated with anti-C9 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>259 publications with C9 and Liver
Uncharacterized Tissue Antibodies	>1 publications with C9 and Uncharacterized Tissue