Rabbit Anti-UBE2D2A Polyclonal Antibody – Cat# MBS6012359

UBE2D2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2D2 antibody detected the UBE2D2 protein (arrow).

UBE2D2A Antibody – Rabbit Polyclonal

Name: UBE2D2A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6012359
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6012359

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s,… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UBE2D2 (Ube2d2a), Polyclonal Antibody

Full Product Name

UBE2D2, CT (UBE2D2, UBC4, UBC5B, UBCH4, UBCH5B, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17kD 2, Ubiquitin-protein ligase D2)

Product Gene Name

anti-Ube2d2a antibody

Product Synonym Names

Anti -UBE2D2, CT (UBE2D2, UBC4, UBC5B, UBCH4, UBCH5B, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17kD 2, Ubiquitin-protein ligase D2)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

16,735 Da

Chromosome Location

Chromosome: 18; NC_000084.6 (35771559..35807172). Location: 18 B2; 18

3D Structure

ModBase 3D Structure for P62838

Immunogen

UBE2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2.

Product Categories/Family for anti-Ube2d2a antibody

Antibodies; Abs to Ubiquitin Ligases

Applications Tested/Suitable for anti-Ube2d2a antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-Ube2d2a antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-Ube2d2a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ube2d2a purchase

MBS6012359 is an antibody targeting Ube2d2a. Also known as UBE2D2, CT (UBE2D2, UBC4, UBC5B, UBCH4, UBCH5B, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2(17)KB 2, Ubiquitin-conjugating enzyme E2-17kD 2, Ubiquitin-protein ligase D2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Ube2d2a. It may not necessarily be applicable to this product.

NCBI GI #

9910600

NCBI GeneID

56550

NCBI Accession #

NP_064296.1

UniProt Primary Accession #

P62838

UniProt Secondary Accession #

P51669

UniProt Related Accession #

P62838

GenBank Nucleotide #

NM_019912.2

NCBI Official Full Name

ubiquitin-conjugating enzyme E2 D2

NCBI Official Synonym Full Names

ubiquitin-conjugating enzyme E2D 2A

NCBI Official Symbol

Ube2d2a

NCBI Official Synonym Symbols

ubc4; Ubc2e; Ube2d2; 1500034D03Rik

UniProt Protein Name

Ubiquitin-conjugating enzyme E2 D2

UniProt Synonym Protein Names

Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2

UniProt Gene Name

Ube2d2

UniProt Synonym Gene Names

Ubc4; Ubch4; Ubch5b; Ube2d2a

UniProt Entry Name

UB2D2_MOUSE

NCBI Protein Information

ubiquitin-conjugating enzyme E2 D2; E2(17)KB 2; ubiquitin-protein ligase D2; ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2(17)KB 2; ubiquitin-conjugating enzyme E2-17 kDa 2

UniProt Comments for Ube2d2a

UBE2D2: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3. Belongs to the ubiquitin-conjugating enzyme family.

Protein type: EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Cellular Component: protein complex; ubiquitin ligase complex

Molecular Function: protein binding; nucleotide binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: protein polyubiquitination; protein ubiquitination

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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