• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CGRP Positive Control

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5401247

MBS5401247 is a positive control targeting CGRP. Western Blot Positive Control Calcitonin gene-related peptide 1 Antibody More details

$370 / 5 Applications +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CGRP, Positive Control
Full Product Name
CGRP Positive Control
Product Gene Name
CGRP positive control
Concentration
The concentration of the sample is empirically set so that 20 ul per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. (lot specific)
Preparation and Storage
Store at -20 degree C for long term storage
Matching Pairs
Antibody: CGRP (MBS5401074)
Positive Control: CGRP (MBS5401247)
Matching Pairs
Antibody: CGRP (MBS5401075)
Positive Control: CGRP (MBS5401247)
Molecular Weight
15,141 Da
3D Structure
ModBase 3D Structure for Q99JA0

Product Categories/Family for CGRP positive control

Biomolecule
Applications Tested/Suitable for CGRP positive control
Western Blot (WB)

Other Notes

Small volumes of CGRP positive control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CGRP. It may not necessarily be applicable to this product.

NCBI GI #
76880463
NCBI GeneID
12310
NCBI Accession #
NP_001029126.1
UniProt Primary Accession #
Q99JA0
UniProt Related Accession #
P70160; Q99JA0
GenBank Nucleotide #
NM_001033954.3
NCBI Official Full Name
calcitonin gene-related peptide 1 isoform Cgrp preproprotein
NCBI Official Synonym Full Names
calcitonin/calcitonin-related polypeptide, alpha
NCBI Official Symbol
Calca
NCBI Official Synonym Symbols
CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1
UniProt Protein Name
Calcitonin gene-related peptide 1
UniProt Synonym Protein Names
Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I
Protein Family
Calcitonin gene-related peptide
UniProt Gene Name
Calca
UniProt Synonym Gene Names
Calc; CGRP-I
UniProt Entry Name
CALCA_MOUSE
NCBI Protein Information
calcitonin gene-related peptide 1

NCBI Summary for CGRP

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity. [provided by RefSeq, Mar 2015]
Show more

UniProt Comments for CGRP

CALCA iso3: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: axon; cell soma; cytoplasm; extracellular region; extracellular space; intracellular; neuron projection; nucleus; terminal button

Molecular Function: calcitonin receptor binding; receptor binding

Biological Process: adenylate cyclase activation; cellular calcium ion homeostasis; detection of temperature stimulus involved in sensory perception of pain; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; inflammatory response; negative regulation of blood pressure; negative regulation of neurological process; negative regulation of ossification; negative regulation of smooth muscle contraction; neuromuscular junction development; neuropeptide signaling pathway; positive regulation of cell adhesion; positive regulation of ossification; regulation of blood pressure; regulation of heart contraction; regulation of heart rate; regulation of systemic arterial blood pressure by neurological process; response to heat; response to pain; sperm capacitation; vasodilation; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure
Show more

Research Articles on CGRP

1. SHH may affect alveolar bone healing by interacting with CGRP-positive sensory neurons and thus regulate the socket's healing process after tooth extraction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CGRP positive control

 Products by Pathway  Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with CGRP positive control

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >14 publications with CGRP and Inflammation
 Lung Diseases Antibodies  >12 publications with CGRP and Lung Diseases
 Hypertension Antibodies  >6 publications with CGRP and Hypertension
 Pain Antibodies  >6 publications with CGRP and Pain
 Migraine Disorders Antibodies  >5 publications with CGRP and Migraine Disorders
 Headache Antibodies  >5 publications with CGRP and Headache
 Neurogenic Inflammation Antibodies  >4 publications with CGRP and Neurogenic Inflammation
 Kidney Diseases Antibodies  >3 publications with CGRP and Kidney Diseases
 Necrosis Antibodies  >3 publications with CGRP and Necrosis
 Migraine without Aura Antibodies  >2 publications with CGRP and Migraine without Aura

Organs/Tissues associated with CGRP positive control

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >24 publications with CGRP and Blood
 Thyroid Antibodies  >11 publications with CGRP and Thyroid
 Brain Antibodies  >9 publications with CGRP and Brain
 Spinal Cord Antibodies  >4 publications with CGRP and Spinal Cord
 Embryonic Tissue Antibodies  >2 publications with CGRP and Embryonic Tissue
 Bone Marrow Antibodies  >1 publications with CGRP and Bone Marrow
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000