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FOLR1 Positive Control

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5400704

Overview: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH… More details

$370 / 5 Applications +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FOLR1, Positive Control
Full Product Name
FOLR1 Positive Control
Product Gene Name
Product Synonym Names
Western Blot Positive Control Folate receptor Alpha; adult antibody; Adult folate binding protein antibody; FBP antibody; Folate Receptor 1 Adult antibody; Folate receptor 1 antibody; Folate receptor alpha antibody; Folate receptor antibody; FOLR antibody; FOLR1 antibody; FR alpha antibody; KB cells FBP antibody; MOV18 antibody; Ovarian cancer associated antigen antibody; Ovarian tumor associated antigen MOv18 antibody
Preparation and Storage
Store at -20 degree C for long term storage.
Molecular Weight
29,449 Da
3D Structure
ModBase 3D Structure for P35846
Immunogen
Purified protein.
Molecular Function
Receptor
Subcellular Location
Cell Membrane; Cytoplasmic Vesicle; Endosome; Membrane; Secreted
Applications Tested/Suitable for FOLR1 positive control
Western Blot (WB)
Application Notes for FOLR1 positive control
WB: 1:500

Other Notes

Small volumes of FOLR1 positive control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOLR1 purchase

MBS5400704 is a positive control targeting FOLR1.

Additional Details

NCBI/Uniprot data below describe general gene information for FOLR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
folate receptor alpha
NCBI Official Synonym Full Names
folate receptor 1 (adult)
NCBI Official Symbol
Folr1
NCBI Official Synonym Symbols
FBP1; Folbp1; Folbp-1
UniProt Protein Name
Folate receptor alpha
UniProt Synonym Protein Names
Folate receptor 1; Folate-binding protein 1
Protein Family
UniProt Gene Name
Folr1
UniProt Synonym Gene Names
Fbp1; Folbp1; FR-alpha
NCBI Protein Information
folate receptor alpha

UniProt Comments for FOLR1

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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