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PTBP2 Positive Control

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5401311

Western Blot Positive Control Polypyrimidine tract-binding protein 2/PTBP2 Antibody More details

$370 / 5 Applications +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTBP2, Positive Control
Full Product Name
PTBP2 Positive Control
Product Gene Name
Concentration
The concentration of the sample is empirically set so that 20 ul per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. (lot specific)
Preparation and Storage
Store at -20 degree C for long term storage
Matching Pairs
Antibody: PTBP2 (MBS5401475)
Positive Control: PTBP2 (MBS5401311)
Matching Pairs
Antibody: PTBP2 (MBS5401476)
Positive Control: PTBP2 (MBS5401311)
Molecular Weight
38,336 Da
OMIM
AF176085 mRNA
3D Structure
ModBase 3D Structure for Q9UKA9
Immunogen
Purified Polypyrimidine tract-binding protein 2/PTBP2

Product Categories/Family for PTBP2 positive control

Applications Tested/Suitable for PTBP2 positive control
Western Blot (WB)

Other Notes

Small volumes of PTBP2 positive control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTBP2 purchase

MBS5401311 is a positive control targeting PTBP2.

Additional Details

NCBI/Uniprot data below describe general gene information for PTBP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
polypyrimidine tract-binding protein 2 isoform 1
NCBI Official Synonym Full Names
polypyrimidine tract binding protein 2
NCBI Official Symbol
PTBP2
NCBI Official Synonym Symbols
nPTB; PTBLP; brPTB
UniProt Protein Name
Polypyrimidine tract-binding protein 2
UniProt Synonym Protein Names
Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; PTB-like protein
UniProt Gene Name
PTBP2
UniProt Synonym Gene Names
NPTB; PTB; PTBLP
NCBI Protein Information
polypyrimidine tract-binding protein 2

NCBI Summary for PTBP2

The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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UniProt Comments for PTBP2

PTBP2: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre- mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing; RNA-binding

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: cell soma; growth cone; spliceosomal complex

Molecular Function: mRNA binding; RNA binding

Biological Process: cerebellum development; mRNA splice site selection; negative regulation of RNA splicing; regulation of neural precursor cell proliferation; spinal cord development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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