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GPR17 Human Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1880046

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G (i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.[UniProtKB/Swiss-Prot Function] More details

$1320 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR17, Protein
Full Product Name
Human GPR17 full length protein-synthetic nanodisc
Product Gene Name
Product Synonym Names
Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12
Host
HEK293
Form/Format
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing).
Molecular Weight
40,989 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (128403439..128410213). Location: 2q21
OMIM
603071
3D Structure
ModBase 3D Structure for Q13304

Other Notes

Small volumes of GPR17 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR17 purchase

MBS1880046 is a protein targeting GPR17. Also known as Human GPR17 full length protein-synthetic nanodisc. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR17. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uracil nucleotide/cysteinyl leukotriene receptor isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 17
NCBI Official Symbol
GPR17
UniProt Protein Name
Uracil nucleotide/cysteinyl leukotriene receptor
UniProt Synonym Protein Names
G-protein coupled receptor 17; P2Y-like receptor; R12
UniProt Gene Name
GPR17
UniProt Synonym Gene Names
UDP/CysLT receptor
UniProt Entry Name
GPR17_HUMAN
NCBI Protein Information
uracil nucleotide/cysteinyl leukotriene receptor; R12; P2Y-like receptor; UDP/CysLT receptor; G-protein coupled receptor 17

UniProt Comments for GPR17

GPR17: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 2q21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GPR17 protein

 Reference Product  PubMed Publications
 GNA13 protein  >1 publications with GPR17 and GNA13

Organs/Tissues associated with GPR17 protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >25 publications with GPR17 and Brain
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