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GPR3 Human Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1883462

This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated… More details

$1205 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR3, Protein
Full Product Name
Human GPR3-Strep full length protein-synthetic nanodisc
Product Gene Name
GPR3 protein
Product Synonym Names
ACCA
Host
HEK293
Form/Format
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Molecular Weight
330
OMIM
600241
3D Structure
ModBase 3D Structure for P46089
Tag
C-DYKDDDDK&Strep

Product Categories/Family for GPR3 protein

GPCRDB Class A Rhodopsin-like

Other Notes

Small volumes of GPR3 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR3 purchase

MBS1883462 is a protein targeting GPR3. Also known as Human GPR3-Strep full length protein-synthetic nanodisc. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR3. It may not necessarily be applicable to this product.

NCBI GI #
1170006
NCBI GeneID
2827
NCBI Accession #
P46089.1
UniProt Primary Accession #
P46089
UniProt Secondary Accession #
A8K570
UniProt Related Accession #
P46089
NCBI Official Full Name
G-protein coupled receptor 3
NCBI Official Synonym Full Names
G protein-coupled receptor 3
NCBI Official Symbol
GPR3
NCBI Official Synonym Symbols
ACCA
UniProt Protein Name
G-protein coupled receptor 3
UniProt Synonym Protein Names
ACCA orphan receptor
Protein Family
G-protein coupled receptor
UniProt Gene Name
GPR3
UniProt Synonym Gene Names
ACCA
UniProt Entry Name
GPR3_HUMAN
NCBI Protein Information
G-protein coupled receptor 3; ACCA orphan receptor; adenylate cyclase constitutive activator

UniProt Comments for GPR3

GPR3: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons and neurite outgrowth. Maintains also meiotic arrest in oocytes. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Cell cycle regulation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.1-p35

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding

Biological Process: elevation of cytosolic calcium ion concentration; regulation of meiosis; positive regulation of cAMP metabolic process; G-protein signaling, adenylate cyclase activating pathway
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Research Articles on GPR3

1. Gpr3 stimulates Abeta production via interactions with APP and beta-arrestin2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GPR3 protein

 Reference Product  PubMed Publications
 GPR4 protein  >4 publications with GPR3 and GPR4

Pathways associated with GPR3 protein

 Products by Pathway  Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with GPR3 protein

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >3 publications with GPR3 and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with GPR3 and Kidney Diseases
 Inflammation Antibodies  >1 publications with GPR3 and Inflammation

Organs/Tissues associated with GPR3 protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with GPR3 and Brain
 Muscle Antibodies  >3 publications with GPR3 and Muscle
 Testis Antibodies  >3 publications with GPR3 and Testis
 Eye Antibodies  >2 publications with GPR3 and Eye
 Uterus Antibodies  >1 publications with GPR3 and Uterus
 Bone Antibodies  >1 publications with GPR3 and Bone
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