Holo Transferrin (HAN_2g338) Protein

MyBioSource is the leading supplier of Human Holo Transferrin from human serum, used for cell culture, medical research and manufacturing of clinical assays for iron deficiencies and disorders of the immune system.

Custom preparations, technical support, bulk quantities and aliquoting available.

Purification procedures include selective size exclusion, ion exchange chromatography and gel fitration for transferrin products.

Ultra Pure Human Holo Transferrin >99% pure available upon request.

Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Transferrin (TF) is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin(TF) to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).

Human Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Transferrin is also associated with the innate immune system. Human Transferrin is found in the mucosa and binds iron, thus creating an environment low in free iron, where few bacteria are able to survive.

Small volumes of HAN_2g338 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS173195 is a protein targeting HAN_2g338. Also known as Holo Transferrin, Human Serum.