MRGX1 Human Protein

Name: MRGX1 Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1883511
Price: 1205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1883511

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide… More details

$1205 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MRGX1, Protein

Full Product Name

Human MRGX1-Strep full length protein-synthetic nanodisc

Product Gene Name

MRGX1 protein

Product Synonym Names

GPCR; MGRG2; MRGX1; SNSR4

Host

HEK293

Form/Format

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Molecular Weight

36,250 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (18955360..18956549, complement). Location: 11p15.1; 11

OMIM

607227

3D Structure

ModBase 3D Structure for Q96LB2

Tag

C-DYKDDDDK&Strep

Product Categories/Family for MRGX1 protein

Full Length Transmembrane Proteins; GPCR; Transmembrane; Druggable Genome

Other Notes

Small volumes of MRGX1 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRGX1 purchase

MBS1883511 is a protein targeting MRGX1. Also known as Human MRGX1-Strep full length protein-synthetic nanodisc. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for MRGX1. It may not necessarily be applicable to this product.

NCBI GI #

125660451

NCBI GeneID

259249

NCBI Accession #

NP_671732.3

UniProt Primary Accession #

Q96LB2

UniProt Secondary Accession #

Q4V9L2; Q8TDD8; Q8TDD9

UniProt Related Accession #

Q96LB2

GenBank Nucleotide #

NM_147199.3

NCBI Official Full Name

mas-related G-protein coupled receptor member X1

NCBI Official Synonym Full Names

MAS-related GPR, member X1

NCBI Official Symbol

MRGPRX1

NCBI Official Synonym Symbols

GPCR; MRGX1; SNSR4

UniProt Protein Name

Mas-related G-protein coupled receptor member X1

UniProt Synonym Protein Names

Sensory neuron-specific G-protein coupled receptor 3/4

UniProt Gene Name

MRGPRX1

UniProt Synonym Gene Names

MRGX1; SNSR3; SNSR4

UniProt Entry Name

MRGX1_HUMAN

NCBI Protein Information

mas-related G-protein coupled receptor member X1; G protein-coupled receptor MRGX1; G protein-coupled receptor SNSR3; sensory neuron-specific G-protein coupled receptor 3/4

UniProt Comments for MRGX1

MRGPRX1: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in an histamine-independent manner. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.1|11

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; acute-phase response

Research Articles on MRGX1

1. analysis of the functional interactions between MRGPR-X1 and TRPV1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.