TAAR1 Human Protein

Name: TAAR1 Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1883640
Price: 1205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1883640

The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine,… More details

$1205 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAAR1, Protein

Full Product Name

Human TAAR1-Strep full length protein-synthetic nanodisc

Product Gene Name

TAAR1 protein

Product Synonym Names

TA1; TAR1; TRAR1

Host

HEK293

Form/Format

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Molecular Weight

39,092 Da

OMIM

609333

3D Structure

ModBase 3D Structure for Q96RJ0

Tag

C-DYKDDDDK&Strep

Product Categories/Family for TAAR1 protein

Full Length Transmembrane Proteins; GPCR; Transmembrane; Druggable Genome

Other Notes

Small volumes of TAAR1 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAAR1 purchase

MBS1883640 is a protein targeting TAAR1. Also known as Human TAAR1-Strep full length protein-synthetic nanodisc. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for TAAR1. It may not necessarily be applicable to this product.

NCBI GI #

21264324

NCBI GeneID

134864

NCBI Accession #

NP_612200.1

UniProt Primary Accession #

Q96RJ0

UniProt Secondary Accession #

Q2M1W5; Q3MIH8; Q5VUQ1

UniProt Related Accession #

Q96RJ0

GenBank Nucleotide #

NM_138327.1

NCBI Official Full Name

trace amine-associated receptor 1

NCBI Official Synonym Full Names

trace amine associated receptor 1

NCBI Official Symbol

TAAR1

NCBI Official Synonym Symbols

TA1; TAR1; TRAR1

UniProt Protein Name

Trace amine-associated receptor 1

Protein Family

Trace amine-associated receptor

UniProt Gene Name

TAAR1

UniProt Synonym Gene Names

TA1; TAR1; TRAR1; TaR-1; Trace amine receptor 1

UniProt Entry Name

TAAR1_HUMAN

NCBI Protein Information

trace amine-associated receptor 1; taR-1; trace amine receptor 1

NCBI Summary for TAAR1

TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]

UniProt Comments for TAAR1

TAAR1: Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on TAAR1

1. an increase in TAAR1 receptor expression is concomitant with lymphocyte immune activation, suggesting a possible role for TAAR1 in the generation or regulation of an immune response

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TAAR1 protein

Reference Product	PubMed Publications
ADRB2 protein	>3 publications with TAAR1 and ADRB2
ADRB1 protein	>1 publications with TAAR1 and ADRB1

Pathways associated with TAAR1 protein

Products by Pathway	Pathway Diagram
Amine Ligand-binding Receptors Pathway antibodies	Amine Ligand-binding Receptors Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies	Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with TAAR1 protein

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>6 publications with TAAR1 and Mental Disorders
Nervous System Diseases Antibodies	>4 publications with TAAR1 and Nervous System Diseases
Movement Disorders Antibodies	>3 publications with TAAR1 and Movement Disorders
Attention Deficit Disorder with Hyperactivity Antibodies	>3 publications with TAAR1 and Attention Deficit Disorder with Hyperactivity
Catalepsy Antibodies	>2 publications with TAAR1 and Catalepsy
Hypothermia Antibodies	>2 publications with TAAR1 and Hypothermia
Heart Diseases Antibodies	>1 publications with TAAR1 and Heart Diseases
Nerve Degeneration Antibodies	>1 publications with TAAR1 and Nerve Degeneration
Arrhythmias, Cardiac Antibodies	>1 publications with TAAR1 and Arrhythmias, Cardiac
Headache Antibodies	>1 publications with TAAR1 and Headache

Organs/Tissues associated with TAAR1 protein

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>1 publications with TAAR1 and Stomach