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UTS2R Human Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS189893

High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function] More details

$1320 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UTS2R, Protein
Full Product Name
Human UTS2R full length protein-synthetic nanodisc
Product Gene Name
UTS2R protein
Product Synonym Names
GPR14; UR-2-R; UTR; UTR2
Host
HEK293
Form/Format
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing).
Molecular Weight
389
OMIM
600896
3D Structure
ModBase 3D Structure for Q9UKP6

Product Categories/Family for UTS2R protein

FLP 489; Full Length Transmembrane Proteins

Other Notes

Small volumes of UTS2R protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UTS2R purchase

MBS189893 is a protein targeting UTS2R. Also known as Human UTS2R full length protein-synthetic nanodisc. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for UTS2R. It may not necessarily be applicable to this product.

NCBI GI #
8928474
NCBI GeneID
2837
NCBI Accession #
Q9UKP6.1
UniProt Primary Accession #
Q9UKP6
UniProt Secondary Accession #
B2RMV8
UniProt Related Accession #
Q9UKP6
NCBI Official Full Name
Urotensin-2 receptor
NCBI Official Synonym Full Names
urotensin 2 receptor
NCBI Official Symbol
UTS2R
NCBI Official Synonym Symbols
UTR; UTR2; GPR14; UR-2-R
UniProt Protein Name
Urotensin-2 receptor
UniProt Synonym Protein Names
G-protein coupled receptor 14; Urotensin II receptor; UR-II-R
Protein Family
Urotensin-2 receptor
UniProt Gene Name
UTS2R
UniProt Synonym Gene Names
GPR14; UR-2-R; UR-II-R
UniProt Entry Name
UR2R_HUMAN
NCBI Protein Information
urotensin-2 receptor; UR-II-R; urotensin II receptor; G protein-coupled receptor 14; G-protein coupled receptor 14

UniProt Comments for UTS2R

UTS2R: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: recycling endosome; membrane; early endosome; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; urotensin II receptor activity

Biological Process: response to drug; G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; positive regulation of fibroblast proliferation; positive regulation of circadian sleep/wake cycle, REM sleep; negative regulation of glomerular filtration; regulation of vasodilation; blood circulation; positive regulation of vasoconstriction; negative regulation of blood pressure; signal transduction; positive regulation of cell growth; positive regulation of blood pressure
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Research Articles on UTS2R

1. UTR protein and mRNA levels were increased in colon cancer cell lines and in colon adenoma and adenocarcinoma. UTR appears to be involved in the regulation of colon cancer cell invasion and motility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with UTS2R protein

 Reference Product  PubMed Publications
 UTS2D protein  >9 publications with UTS2R and UTS2D
 UTS2 protein  >4 publications with UTS2R and UTS2

Pathways associated with UTS2R protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with UTS2R protein

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >63 publications with UTS2R and Cardiovascular Diseases
 Atherosclerosis Antibodies  >14 publications with UTS2R and Atherosclerosis
 Hypertrophy Antibodies  >12 publications with UTS2R and Hypertrophy
 Inflammation Antibodies  >8 publications with UTS2R and Inflammation
 Liver Diseases Antibodies  >7 publications with UTS2R and Liver Diseases
 Carcinoma Antibodies  >7 publications with UTS2R and Carcinoma
 Arteriosclerosis Antibodies  >7 publications with UTS2R and Arteriosclerosis
 Liver Cirrhosis Antibodies  >4 publications with UTS2R and Liver Cirrhosis
 Lung Neoplasms Antibodies  >2 publications with UTS2R and Lung Neoplasms
 Metaplasia Antibodies  >1 publications with UTS2R and Metaplasia

Organs/Tissues associated with UTS2R protein

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >4 publications with UTS2R and Ovary
 Embryonic Tissue Antibodies  >2 publications with UTS2R and Embryonic Tissue
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