Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein
Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development.
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Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
SOHLH1: Transcription factor expressed in undifferentiated spermatogonia required for spermatogonial development. Genetic variations in SOHLH1 may be associated with non-obstructive azoospermia. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Cellular Component: cytoplasm; nucleus
Molecular Function: transcription factor activity
Biological Process: cell differentiation; oogenesis; ovarian follicle development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of gene expression; spermatogenesis
Protein type: Transcription factor
Cellular Component: cytoplasm; nucleus
Molecular Function: transcription factor activity
Biological Process: cell differentiation; oogenesis; ovarian follicle development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of gene expression; spermatogenesis
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
SOHLH2: Probable transcription factor, which may be involved in spermatogenesis and oogenesis. 3 isoforms of the human protein are produced by alternative splicing.
Cellular Component: nucleus
Biological Process: oocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; primary ovarian follicle growth; regulation of gene expression
Cellular Component: nucleus
Biological Process: oocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; primary ovarian follicle growth; regulation of gene expression
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