Prostate Specific Antigen (PSA) ELISA Kit for Mouse

Name: Mouse PSA ELISA Kit; Prostate Specific Antigen; MyBioSource
Brand: MyBioSource
SKU: MBS034265
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS034265

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of PSAg (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Prostate Specific Antigen (PSA), ELISA Kit

Full Product Name

Mouse Prostate Specific Antigen ELISA Kit

Product Gene Name

PSA elisa kit

Species Reactivity

Mouse

Assay Type

Quantitative Sandwich

Detection Range

0.25ng/ml-8ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

28,741 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (51358171..51364020). Location: 19q13.41

OMIM

176820

3D Structure

ModBase 3D Structure for P07288

Other Notes

Small volumes of PSA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSA purchase

MBS034265 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostate Specific Antigen (PSA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PSA. The ELISA analytical biochemical technique of the MBS034265 kit is based on PSA antibody-PSA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PSA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PSA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PSA. It may not necessarily be applicable to this product.

NCBI GI #

4502173

NCBI GeneID

354

NCBI Accession #

NP_001639.1

UniProt Primary Accession #

P07288

UniProt Secondary Accession #

Q15096; Q16272; Q86TG8; Q8IXI4; C9JXH3; G3V0H4; G3XAE3

UniProt Related Accession #

P07288

GenBank Nucleotide #

NM_001648.2

NCBI Official Full Name

prostate-specific antigen isoform 1 preproprotein

NCBI Official Synonym Full Names

kallikrein-related peptidase 3

NCBI Official Symbol

KLK3

NCBI Official Synonym Symbols

APS; PSA; hK3; KLK2A1

UniProt Protein Name

Prostate-specific antigen

UniProt Synonym Protein Names

Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase

Protein Family

Prostate-specific antigen

UniProt Gene Name

KLK3

UniProt Synonym Gene Names

APS; PSA; Seminin

UniProt Entry Name

KLK3_HUMAN

NCBI Protein Information

prostate-specific antigen; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen

NCBI Summary for PSA

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for PSA

PSA: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. Forms heterodimer with SERPINA5. Inhibited by SERPINA5. Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein type: EC 3.4.21.77; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region; nucleus

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: negative regulation of angiogenesis; cellular protein metabolic process; proteolysis

Research Articles on PSA

1. PSA levels are associated with a G/A polymorphism only in healthy controls; the transition, however, is not associated with PSA levels of benign prostatic hypertrophy and cancer patients, nor is it a risk factor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PSA elisa kit

Reference Product	PubMed Publications
TP53 elisa kit	>2 publications with PSA and TP53
ERBB2 elisa kit	>2 publications with PSA and ERBB2
IL6 elisa kit	>1 publications with PSA and IL6

Pathways associated with PSA elisa kit

Products by Pathway	Pathway Diagram
Androgen Receptor Signaling Pathway antibodies	Androgen Receptor Signaling Pathway Diagram
Coregulation Of Androgen Receptor Activity Pathway antibodies	Coregulation Of Androgen Receptor Activity Pathway Diagram
FOXA1 Transcription Factor Network Pathway antibodies	FOXA1 Transcription Factor Network Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Pathways In Cancer antibodies	Pathways In Cancer Diagram
Prostate Cancer Pathway antibodies	Prostate Cancer Pathway Diagram
Prostate Cancer Pathway antibodies	Prostate Cancer Pathway Diagram
Prostate Cancer Pathway antibodies	Prostate Cancer Pathway Diagram
Regulation Of Androgen Receptor Activity Pathway antibodies	Regulation Of Androgen Receptor Activity Pathway Diagram
Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies	Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram

Diseases associated with PSA elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>86 publications with PSA and Neoplasms
Prostatic Neoplasms Antibodies	>65 publications with PSA and Prostatic Neoplasms
Adenocarcinoma Antibodies	>13 publications with PSA and Adenocarcinoma
Breast Neoplasms Antibodies	>13 publications with PSA and Breast Neoplasms
Hyperplasia Antibodies	>7 publications with PSA and Hyperplasia
Disease Progression Antibodies	>7 publications with PSA and Disease Progression
Neoplasms, Experimental Antibodies	>6 publications with PSA and Neoplasms, Experimental
Ovarian Neoplasms Antibodies	>6 publications with PSA and Ovarian Neoplasms
Kidney Diseases Antibodies	>6 publications with PSA and Kidney Diseases
Neoplasm Metastasis Antibodies	>5 publications with PSA and Neoplasm Metastasis

Organs/Tissues associated with PSA elisa kit

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>112 publications with PSA and Prostate
Salivary Gland Antibodies	>4 publications with PSA and Salivary Gland
Brain Antibodies	>4 publications with PSA and Brain
Bone Antibodies	>3 publications with PSA and Bone
Muscle Antibodies	>2 publications with PSA and Muscle
Nerve Antibodies	>2 publications with PSA and Nerve
Adrenal Gland Antibodies	>1 publications with PSA and Adrenal Gland