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PLA2G2A ELISA Kit for Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2502896

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rabbit PLA2G2A concentrations in serum, plasma and other biological fluids.Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate… More details

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Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PLA2G2A, ELISA Kit
Full Product Name
Rabbit PLA2G2A (Phospholipase A2, Group II A) ELISA Kit
Product Gene Name
PLA2G2A elisa kit
Species Reactivity
Rabbit
Assay Type
Sandwich
Samples
Serum, Plasma, Biological Fluids
Detection Range
1.563-100ng/mL
Sensitivity
Min: 0.938ng/mL; Max: 100ng/mL
Specificity
This kit recognizes natural and recombinant Rabbit PLA2G2A. No significant cross-reactivity or interference between Rabbit PLA2G2A and analogues was observed.
Preparation and Storage
Store at 4 degree C.
Molecular Weight
16,083 Da
OMIM
172411
3D Structure
ModBase 3D Structure for P14555
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of PLA2G2A elisa kit

Rabbit PLA2G2A ELISA Kit – Cat# MBS2502896

Other Notes

Small volumes of PLA2G2A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLA2G2A purchase

MBS2502896 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PLA2G2A, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLA2G2A. The ELISA analytical biochemical technique of the MBS2502896 kit is based on PLA2G2A antibody-PLA2G2A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLA2G2A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLA2G2A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G2A. It may not necessarily be applicable to this product.

NCBI GI #
239915991
NCBI GeneID
5320
NCBI Accession #
NP_001155201.1
UniProt Primary Accession #
P14555
UniProt Secondary Accession #
Q6DN24; Q6IBD9; Q9UCD2; A8K5I7
UniProt Related Accession #
P14555
GenBank Nucleotide #
NM_001161729.1
NCBI Official Full Name
phospholipase A2, membrane associated
NCBI Official Synonym Full Names
phospholipase A2, group IIA (platelets, synovial fluid)
NCBI Official Symbol
PLA2G2A
NCBI Official Synonym Symbols
MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
UniProt Protein Name
Phospholipase A2, membrane associated
UniProt Synonym Protein Names
GIIC sPLA2; Group IIA phospholipase A2; Non-pancreatic secretory phospholipase A2; NPS-PLA2; Phosphatidylcholine 2-acylhydrolase 2A
Protein Family
Phospholipase
UniProt Gene Name
PLA2G2A
UniProt Synonym Gene Names
PLA2B; PLA2L; RASF-A; NPS-PLA2
UniProt Entry Name
PA2GA_HUMAN
NCBI Protein Information
phospholipase A2, membrane associated; GIIC sPLA2; NPS-PLA2; group IIA phospholipase A2; non-pancreatic secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A

NCBI Summary for PLA2G2A

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
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UniProt Comments for PLA2G2A

PLA2G2A: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Belongs to the phospholipase A2 family.

Protein type: Secreted, signal peptide; Phospholipase; Lipid Metabolism - arachidonic acid; Vesicle; Lipid Metabolism - ether lipid; Secreted; Lipid Metabolism - alpha-linolenic acid; Mitochondrial; EC 3.1.1.4; Endoplasmic reticulum; Lipid Metabolism - linoleic acid; Lipid Metabolism - glycerophospholipid

Chromosomal Location of Human Ortholog: 1p35

Cellular Component: extracellular space; endoplasmic reticulum membrane; mitochondrion; endoplasmic reticulum; extracellular region; secretory granule

Molecular Function: phospholipase A2 activity; calcium-dependent phospholipase A2 activity; phospholipid binding; calcium ion binding

Biological Process: defense response to Gram-positive bacterium; phosphatidic acid metabolic process; somatic stem cell maintenance; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; lipid catabolic process; positive regulation of inflammatory response; negative regulation of epithelial cell proliferation

Disease: Colorectal Cancer
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Research Articles on PLA2G2A

1. PLA2G2A gene polymorphisms may modify the risk of esophageal squamous cell carcinoma development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PLA2G2A elisa kit

 Reference Product  PubMed Publications
 PTGS2 elisa kit  >7 publications with PLA2G2A and PTGS2
 PLA2G7 elisa kit  >2 publications with PLA2G2A and PLA2G7
 PTGS1 elisa kit  >2 publications with PLA2G2A and PTGS1

Pathways associated with PLA2G2A elisa kit

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PG Pathway antibodies  Acyl Chain Remodelling Of PG Pathway Diagram
 Acyl Chain Remodelling Of PI Pathway antibodies  Acyl Chain Remodelling Of PI Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram

Diseases associated with PLA2G2A elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >37 publications with PLA2G2A and Inflammation
 Colorectal Neoplasms Antibodies  >25 publications with PLA2G2A and Colorectal Neoplasms
 Heart Diseases Antibodies  >8 publications with PLA2G2A and Heart Diseases
 Atherosclerosis Antibodies  >8 publications with PLA2G2A and Atherosclerosis
 Lung Neoplasms Antibodies  >6 publications with PLA2G2A and Lung Neoplasms
 Necrosis Antibodies  >5 publications with PLA2G2A and Necrosis
 Myocardial Ischemia Antibodies  >5 publications with PLA2G2A and Myocardial Ischemia
 Liver Diseases Antibodies  >4 publications with PLA2G2A and Liver Diseases
 Hyperplasia Antibodies  >4 publications with PLA2G2A and Hyperplasia
 Colitis Antibodies  >4 publications with PLA2G2A and Colitis

Organs/Tissues associated with PLA2G2A elisa kit

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >38 publications with PLA2G2A and Intestine
 Heart Antibodies  >11 publications with PLA2G2A and Heart
 Lung Antibodies  >10 publications with PLA2G2A and Lung
 Stomach Antibodies  >9 publications with PLA2G2A and Stomach
 Liver Antibodies  >7 publications with PLA2G2A and Liver
 Vascular Antibodies  >7 publications with PLA2G2A and Vascular
 Prostate Antibodies  >5 publications with PLA2G2A and Prostate
 Brain Antibodies  >3 publications with PLA2G2A and Brain
 Uterus Antibodies  >3 publications with PLA2G2A and Uterus
 Muscle Antibodies  >2 publications with PLA2G2A and Muscle
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