Rat GM-CSF Active Protein – Cat# MBS692145

GM-CSF Rat Active Protein

Name: GM-CSF Active Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS692145
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692145

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells,… More details

$305 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GM-CSF, Active Protein

Full Product Name

Rat GM-CSF

Product Gene Name

GM-CSF active protein

Product Synonym Names

Recombinant Rat GM-CSF

Sequence

MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISN EFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP P TPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK

Host

E Coli

Species Reactivity

Rat

Form/Format

Lyophilized

Purity/Purification

> 98% by SDS-PAGE and HPLC analysis

Molecular Weight

14.5 kDa

Chromosome Location

Chromosome: 10; NC_005109.3 (39379120..39381430, complement). Location: 10q22

3D Structure

ModBase 3D Structure for P48750

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 0.1 ng/ug of GM-CSF

Biological Activity

The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is <= 0.01 ng/ml, corresponding to a specific activity of >= 1.0 x 108 units/mg.

Product Categories/Family for GM-CSF active protein

Cytokines & Growth Factors

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of GM-CSF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GM-CSF purchase

MBS692145 is an active protein targeting GM-CSF. Also known as Rat GM-CSF. Reactive in Rat. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GM-CSF. It may not necessarily be applicable to this product.

NCBI GI #

449083355

NCBI GeneID

116630

NCBI Accession #

NP_446304.1

UniProt Primary Accession #

P48750

UniProt Related Accession #

P48750

GenBank Nucleotide #

NM_053852.1

NCBI Official Full Name

granulocyte-macrophage colony-stimulating factor

NCBI Official Synonym Full Names

colony stimulating factor 2 (granulocyte-macrophage)

NCBI Official Symbol

Csf2

NCBI Official Synonym Symbols

Gmcsf; Gm-csf

UniProt Protein Name

Granulocyte-macrophage colony-stimulating factor

UniProt Synonym Protein Names

Colony-stimulating factor

Protein Family

Granulocyte colony-stimulating factor receptor

UniProt Gene Name

Csf2

UniProt Synonym Gene Names

Csfgm; GM-CSF; CSF

UniProt Entry Name

CSF2_RAT

NCBI Protein Information

granulocyte-macrophage colony-stimulating factor; CSF

NCBI Summary for GM-CSF

plays a role in alveolar epithelial fluid transport [RGD, Feb 2006]

UniProt Comments for GM-CSF

Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes

By similarity.

Subunit structure: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the GM-CSF family.

Research Articles on GM-CSF

1. Expression of SCF+GM-CSF after hepatectomy can contribute to biliary remodeling (e.g., post-transplantation) by functional deregulation of the activity of key signaling intermediates involved in cell expansion and multipotent differentiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GM-CSF active protein

Reference Product	PubMed Publications
Il6 active protein	>22 publications with GM-CSF and Il6
Il4 active protein	>17 publications with GM-CSF and Il4
Ccl2 active protein	>16 publications with GM-CSF and Ccl2
Il5 active protein	>10 publications with GM-CSF and Il5
Il2 active protein	>9 publications with GM-CSF and Il2
Csf2rb active protein	>8 publications with GM-CSF and Csf2rb
Il7 active protein	>4 publications with GM-CSF and Il7
Cd80 active protein	>2 publications with GM-CSF and Cd80
Stat3 active protein	>2 publications with GM-CSF and Stat3
Fos active protein	>2 publications with GM-CSF and Fos

Pathways associated with GM-CSF active protein

Products by Pathway	Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
Fc Epsilon RI Signaling Pathway antibodies	Fc Epsilon RI Signaling Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram

Diseases associated with GM-CSF active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>32 publications with GM-CSF and Inflammation
Necrosis Antibodies	>23 publications with GM-CSF and Necrosis
Neoplasms Antibodies	>21 publications with GM-CSF and Neoplasms
Lung Diseases Antibodies	>8 publications with GM-CSF and Lung Diseases
Breast Neoplasms Antibodies	>5 publications with GM-CSF and Breast Neoplasms
Carcinoma Antibodies	>3 publications with GM-CSF and Carcinoma
Leukemia, Myeloid, Acute Antibodies	>3 publications with GM-CSF and Leukemia, Myeloid, Acute
Lung Neoplasms Antibodies	>3 publications with GM-CSF and Lung Neoplasms
Arthritis, Rheumatoid Antibodies	>2 publications with GM-CSF and Arthritis, Rheumatoid
Neoplasm Invasiveness Antibodies	>2 publications with GM-CSF and Neoplasm Invasiveness