Human AOC3 Recombinant Protein – Cat# MBS189531

Figure 1. Human AOC3 Protein, His Tag on SDS-PAGE under reducing condition.

AOC3 Human Recombinant Protein

Name: AOC3 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS189531
Price: 290 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS189531

Recombinant human AOC3 Protein with N-terminal 6×His tagThis gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone… More details

$290 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AOC3, Recombinant Protein

Full Product Name

Human AOC3 Protein, His Tag

Product Gene Name

AOC3 recombinant protein

Product Synonym Names

HPAO; SSAO; VAP1; VAP-1

Sequence

6×His tag AOC3(Arg28 -Asn763)

Host

HEK293

Form/Format

Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.

Purity/Purification

Purified from cell culture supernatant by affinity chromatography
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing).

Molecular Weight

763

OMIM

603735

3D Structure

ModBase 3D Structure for Q16853

Tag

N-6×His Tag

Product Categories/Family for AOC3 recombinant protein

ECD 1182; ECD Proteins

Other Notes

Small volumes of AOC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AOC3 purchase

MBS189531 is a recombinant protein targeting AOC3. Also known as Human AOC3 Protein, His Tag. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for AOC3. It may not necessarily be applicable to this product.

NCBI GI #

2501336

NCBI GeneID

8639

NCBI Accession #

Q16853.3

UniProt Primary Accession #

Q16853

UniProt Secondary Accession #

Q45F94; B2RCI5; K7ESB3; L0L8N9

UniProt Related Accession #

Q16853

NCBI Official Full Name

Membrane primary amine oxidase

NCBI Official Synonym Full Names

amine oxidase, copper containing 3

NCBI Official Symbol

AOC3

NCBI Official Synonym Symbols

HPAO; SSAO; VAP1; VAP-1

UniProt Protein Name

Membrane primary amine oxidase

UniProt Synonym Protein Names

Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1

Protein Family

Allene oxide cyclase

UniProt Gene Name

AOC3

UniProt Synonym Gene Names

VAP1; SSAO; VAP-1

UniProt Entry Name

AOC3_HUMAN

NCBI Protein Information

membrane primary amine oxidase; copper amine oxidase; placenta copper monamine oxidase; semicarbazide-sensitive amine oxidase; amine oxidase, copper containing 3 (vascular adhesion protein 1)

NCBI Summary for AOC3

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

UniProt Comments for AOC3

AOC3: Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin- independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. Belongs to the copper/topaquinone oxidase family.

Protein type: Cell adhesion; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Other Amino Acids Metabolism - beta-alanine; Membrane protein, integral; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; EC 1.4.3.21

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cell surface; microvillus; cytoplasm; plasma membrane; integral to membrane

Molecular Function: amine oxidase activity; protein binding; protein homodimerization activity; copper ion binding; protein heterodimerization activity; cation channel activity; calcium ion binding; quinone binding

Biological Process: response to antibiotic; amine metabolic process; cell adhesion; inflammatory response; cation transport

Research Articles on AOC3

1. Serum VAP-1 predicts mortality independently and improves risk stratification in colorectal cancer subjects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with AOC3 recombinant protein

Products by Pathway	Pathway Diagram
Glycine, Serine And Threonine Metabolism Pathway antibodies	Glycine, Serine And Threonine Metabolism Pathway Diagram
Glycine, Serine And Threonine Metabolism Pathway antibodies	Glycine, Serine And Threonine Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Phenylalanine Metabolism Pathway antibodies	Phenylalanine Metabolism Pathway Diagram
Phenylalanine Metabolism Pathway antibodies	Phenylalanine Metabolism Pathway Diagram
Tyrosine Metabolism Pathway antibodies	Tyrosine Metabolism Pathway Diagram
Tyrosine Metabolism Pathway antibodies	Tyrosine Metabolism Pathway Diagram
Beta-Alanine Metabolism Pathway antibodies	Beta-Alanine Metabolism Pathway Diagram
Beta-Alanine Metabolism Pathway antibodies	Beta-Alanine Metabolism Pathway Diagram
Phenylethylamine Degradation I Pathway antibodies	Phenylethylamine Degradation I Pathway Diagram

Diseases associated with AOC3 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>74 publications with AOC3 and Inflammation
Cardiovascular Diseases Antibodies	>33 publications with AOC3 and Cardiovascular Diseases
Atherosclerosis Antibodies	>14 publications with AOC3 and Atherosclerosis
Necrosis Antibodies	>11 publications with AOC3 and Necrosis
Disease Models, Animal Antibodies	>9 publications with AOC3 and Disease Models, Animal
Liver Neoplasms Antibodies	>8 publications with AOC3 and Liver Neoplasms
Lung Diseases Antibodies	>7 publications with AOC3 and Lung Diseases
Hyperglycemia Antibodies	>6 publications with AOC3 and Hyperglycemia
Liver Cirrhosis Antibodies	>5 publications with AOC3 and Liver Cirrhosis
Hypertension Antibodies	>5 publications with AOC3 and Hypertension

Organs/Tissues associated with AOC3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>167 publications with AOC3 and Vascular
Liver Antibodies	>31 publications with AOC3 and Liver
Muscle Antibodies	>20 publications with AOC3 and Muscle
Kidney Antibodies	>13 publications with AOC3 and Kidney
Brain Antibodies	>11 publications with AOC3 and Brain
Heart Antibodies	>11 publications with AOC3 and Heart
Adipose Tissue Antibodies	>9 publications with AOC3 and Adipose Tissue
Lung Antibodies	>7 publications with AOC3 and Lung
Connective Tissue Antibodies	>6 publications with AOC3 and Connective Tissue
Umbilical Cord Antibodies	>6 publications with AOC3 and Umbilical Cord