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ARC Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7614881

MBS7614881 is a recombinant protein targeting ARC. Also known as Recombinant Human ARC. Host: E Coli. More details

$495 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARC, Recombinant Protein
Full Product Name
Recombinant Human ARC
Product Gene Name
ARC recombinant protein
Product Synonym Names
ARC; ARC/ARG3.1; Arg3.1; KIAA0278
Host
E Coli
Form/Format
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4
Purity/Purification
Greater than 90% by SDS-PAGE gel analyses
Preparation and Storage
Store at -20 degree C for 12 months as lyophilized; 2-8 degree C for 1 month under sterile conditions after reconstitution
Molecular Weight
45,316 Da
Sequence Positions
1-212
OMIM
612461
3D Structure
ModBase 3D Structure for Q7LC44
Species
Human
Tag
N-terminal His-IF2DI Tag
Reconstitution
Centrifuge the vial at 10,000rpm for 1 minute, reconstitute at 200ug/ml in sterile distilled water
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for ARC recombinant protein
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of ARC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARC. It may not necessarily be applicable to this product.

NCBI GI #
8567330
NCBI GeneID
23237
NCBI Accession #
NP_056008.1
UniProt Primary Accession #
Q7LC44
UniProt Secondary Accession #
Q9UJW6; Q9Y469
UniProt Related Accession #
Q7LC44
GenBank Nucleotide #
NM_015193.4
NCBI Official Full Name
activity-regulated cytoskeleton-associated protein
NCBI Official Synonym Full Names
activity-regulated cytoskeleton-associated protein
NCBI Official Symbol
ARC
NCBI Official Synonym Symbols
Arg3.1
UniProt Protein Name
Activity-regulated cytoskeleton-associated protein
UniProt Synonym Protein Names
ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog; Arg3.1
Protein Family
AAA ATPase forming ring-shaped complexes
UniProt Gene Name
ARC
UniProt Synonym Gene Names
Arg3.1
UniProt Entry Name
ARC_HUMAN
NCBI Protein Information
activity-regulated cytoskeleton-associated protein; ARC; ARC/ARG3.1; activity-regulated gene 3.1 protein homolog

UniProt Comments for ARC

ARG3.1: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Belongs to the ARC/ARG3.1 family.

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; acrosome; plasma membrane; dendritic spine; cell junction; endosome; actin cytoskeleton

Biological Process: anterior/posterior pattern formation; cell migration; regulation of cell morphogenesis; cytoskeleton organization and biogenesis; endocytosis; learning; endoderm development; regulation of neuronal synaptic plasticity
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Research Articles on ARC

1. Results show that in response to DNA damage, p53 total levels increase proportionally to the strength of the damage; however, p53 tetramers are formed at a constant rate under the control of ARC protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ARC recombinant protein

 Reference Product  PubMed Publications
 BDNF recombinant protein  >148 publications with ARC and BDNF
 CCS recombinant protein  >2 publications with ARC and CCS

Pathways associated with ARC recombinant protein

 Products by Pathway  Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram

Diseases associated with ARC recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1675 publications with ARC and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >907 publications with ARC and Cardiovascular Diseases
 Pain Antibodies  >807 publications with ARC and Pain
 Brain Diseases Antibodies  >690 publications with ARC and Brain Diseases
 Cognition Disorders Antibodies  >292 publications with ARC and Cognition Disorders
 Disease Models, Animal Antibodies  >289 publications with ARC and Disease Models, Animal
 Necrosis Antibodies  >279 publications with ARC and Necrosis
 Inflammation Antibodies  >231 publications with ARC and Inflammation
 Neurobehavioral Manifestations Antibodies  >196 publications with ARC and Neurobehavioral Manifestations
 Hypertension Antibodies  >168 publications with ARC and Hypertension

Organs/Tissues associated with ARC recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3170 publications with ARC and Brain
 Bone Antibodies  >1681 publications with ARC and Bone
 Eye Antibodies  >1306 publications with ARC and Eye
 Lung Antibodies  >630 publications with ARC and Lung
 Liver Antibodies  >287 publications with ARC and Liver
 Adrenal Gland Antibodies  >39 publications with ARC and Adrenal Gland
 Uncharacterized Tissue Antibodies  >5 publications with ARC and Uncharacterized Tissue
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