ASRGL1 Recombinant Protein

Name: ASRGL1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS205954
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205954

Isoaspartyl peptidase/L-asparaginase, also known as ASRGL1, is a 308 amino acid protein belonging to the Ntn-hydrolase family. ASRGL1 has been identified as an autoantigenic protein that is present in the mid-piece of sperm after obstruction of the male… More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ASRGL1, Recombinant Protein

Full Product Name

ASRGL1, 1-308aa, Human, His tag, E Coli

Product Gene Name

ASRGL1 recombinant protein

Product Synonym Names

Isoaspartyl peptidase/L-asparaginase; ALP; ALP1; CRASH

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMNPIVVV HGGGAGPISK DRKERVHQGM VRAATVGYGI LREGGSAVDA VEGAVVALED DPEFNAGCGS VLNTNGEVEM DASIMDGKDL SAGAVSAVQC IANPIKLARL VMEKTPHCFL TDQGAAQFAA AMGVPEIPGE KLVTERNKKR LEKEKHEKGA QKTDCQKNLG TVGAVALDCK GNVAYATSTG GIVNKMVGRV GDSPCLGAGG YADNDIGAVS TTGHGESILK VNLARLTLFH IEQGKTVEEA ADLSLGYMKS RVKGLGGLIV VSKTGDWVAK WTSTSMPWAA AKDGKLHFGI DPDDTTITDL P

Host

E Coli

Form/Format

Liquid. In phosphate buffer saline (pH 7.4) containing 10% glycerol, 1mM DTT

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

34.4 kDa (331aa) confirmed by MALDI-TOF

OMIM

AF411076 mRNA

3D Structure

ModBase 3D Structure for Q7L266

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for ASRGL1 recombinant protein

Neuroscience

Applications Tested/Suitable for ASRGL1 recombinant protein

SDS-PAGE

Product References and Citations for ASRGL1 recombinant protein

Herr J C., et al. (1999) Biol Reprod. 61: 428-435.; Bush L A., et al. (2002) Mol Reprod Dev. 62: 233-247.;

Other Notes

Small volumes of ASRGL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASRGL1 purchase

MBS205954 is a recombinant protein targeting ASRGL1. Also known as ASRGL1, 1-308aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ASRGL1. It may not necessarily be applicable to this product.

NCBI GI #

145275202

NCBI GeneID

80150

NCBI Accession #

NP_001077395

UniProt Primary Accession #

Q7L266

UniProt Secondary Accession #

Q567Q4; Q6P1P0; Q8NI34; Q9H6F7; B2R7Q0

UniProt Related Accession #

Q7L266

GenBank Nucleotide #

NM_001083926.1

NCBI Official Full Name

isoaspartyl peptidase/L-asparaginase

NCBI Official Synonym Full Names

asparaginase like 1

NCBI Official Symbol

ASRGL1

NCBI Official Synonym Symbols

ALP; ALP1; CRASH

UniProt Protein Name

Isoaspartyl peptidase/L-asparaginase

UniProt Synonym Protein Names

Asparaginase-like protein 1

Protein Family

Isoaspartyl peptidase/L-asparaginase

UniProt Gene Name

ASRGL1

UniProt Synonym Gene Names

ALP; CRASH

NCBI Protein Information

isoaspartyl peptidase/L-asparaginase

UniProt Comments for ASRGL1

Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.

Research Articles on ASRGL1

1. Our studies suggest that the p.G178R mutation in ASRGL1 leads to photoreceptor degeneration resulting in progressive vision loss.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ASRGL1 recombinant protein

Products by Pathway	Pathway Diagram
Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies	Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Phenylalanine And Tyrosine Catabolism Pathway antibodies	Phenylalanine And Tyrosine Catabolism Pathway Diagram
Asparagine Degradation Pathway antibodies	Asparagine Degradation Pathway Diagram

Diseases associated with ASRGL1 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>5 publications with ASRGL1 and Carcinoma
Adenocarcinoma Antibodies	>2 publications with ASRGL1 and Adenocarcinoma
Breast Neoplasms Antibodies	>2 publications with ASRGL1 and Breast Neoplasms
Prostatic Neoplasms Antibodies	>1 publications with ASRGL1 and Prostatic Neoplasms
Disease Models, Animal Antibodies	>1 publications with ASRGL1 and Disease Models, Animal
Hyperplasia Antibodies	>1 publications with ASRGL1 and Hyperplasia

Organs/Tissues associated with ASRGL1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with ASRGL1 and Brain
Blood Antibodies	>2 publications with ASRGL1 and Blood
Eye Antibodies	>2 publications with ASRGL1 and Eye
Heart Antibodies	>2 publications with ASRGL1 and Heart
Testis Antibodies	>2 publications with ASRGL1 and Testis
Muscle Antibodies	>1 publications with ASRGL1 and Muscle
Liver Antibodies	>1 publications with ASRGL1 and Liver
Lung Antibodies	>1 publications with ASRGL1 and Lung
Prostate Antibodies	>1 publications with ASRGL1 and Prostate
Ovary Antibodies	>1 publications with ASRGL1 and Ovary