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BTLA Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7621469

MBS7621469 is a recombinant protein targeting BTLA. Also known as Recombinant Human BTLA. Host: Mammalian Cells. More details

$180 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BTLA, Recombinant Protein
Full Product Name
Recombinant Human BTLA
Product Gene Name
Product Synonym Names
B- and T-Lymphocyte Attenuator; B- and T-Lymphocyte-Associated Protein; CD272; BTLA
Sequence
Lys31-Leu1 50
Host
Mammalian Cells
Form/Format
Lyophilized from a 0.2um filtered solution of 20mM PB, 150mM NaCl, pH7.4
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
The lyophilized protein is stable at -20 degree C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 degree C for 3 months or 1 week at 2 to 8 degree C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.
Molecular Weight
32,834 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (112182813..112218408, complement). Location: 3q13.2
OMIM
607925
3D Structure
ModBase 3D Structure for Q7Z6A9
Species
Human
Endotoxin
< 1 EU/ug as determined by LAL test.
Tag
C-terminal His Tag
Reconstitution
Centrifuge the vial at 10000rpm for 30s before opening, reconstitute in sterile distilled water to a concentration of 0.1-1mg/ml by gently pipetting 2-3 times, don't vortex.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for BTLA recombinant protein
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of BTLA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BTLA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
B- and T-lymphocyte attenuator isoform 2
NCBI Official Synonym Full Names
B and T lymphocyte associated
NCBI Official Symbol
BTLA
NCBI Official Synonym Symbols
BTLA1; CD272
UniProt Protein Name
B- and T-lymphocyte attenuator
UniProt Synonym Protein Names
B- and T-lymphocyte-associated protein
UniProt Gene Name
BTLA
UniProt Entry Name
BTLA_HUMAN
NCBI Protein Information
B- and T-lymphocyte attenuator; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein

NCBI Summary for BTLA

This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
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UniProt Comments for BTLA

BTLA: Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: receptor activity

Biological Process: T cell costimulation; negative regulation of alpha-beta T cell proliferation; immune response-regulating cell surface receptor signaling pathway; negative regulation of B cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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