Human CCL7 Recombinant Protein – Cat# MBS1883981

Figure 1. Human CCL7 Protein, hFc Tag on SDS-PAGE under reducing condition.

CCL7 Human Recombinant Protein

Name: CCL7 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1883981
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1883981

This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The… More details

$295 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CCL7, Recombinant Protein

Full Product Name

Human CCL7 Protein, hFc Tag

Product Gene Name

CCL7 recombinant protein

Product Synonym Names

FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7; Recombinant human CCL7 Protein with C-terminal human Fc tag

Sequence

CCL7 (Gln24-Leu 99) hFc (Glu99-Ala 330)

Host

HEK293

Form/Format

Lyophilized from sterile PBS, pH 7.4. Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Purity/Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Molecular Weight

11,200 Da

OMIM

158106

3D Structure

ModBase 3D Structure for P80098

Tag

C-Human Fc

Product Categories/Family for CCL7 recombinant protein

ECD Proteins

Other Notes

Small volumes of CCL7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL7 purchase

MBS1883981 is a recombinant protein targeting CCL7. Also known as Human CCL7 Protein, hFc Tag. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL7. It may not necessarily be applicable to this product.

NCBI GI #

313708

NCBI GeneID

NCBI Accession #

CAA51055.1

UniProt Primary Accession #

P80098

UniProt Secondary Accession #

Q569J6

NCBI Official Full Name

monocyte chemotactic protein-3

UniProt Protein Name

C-C motif chemokine 7

UniProt Synonym Protein Names

Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL7

UniProt Synonym Gene Names

MCP3; SCYA6; SCYA7; MCP-3

UniProt Entry Name

CCL7_HUMAN

UniProt Comments for CCL7

CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; cytoskeleton organization and biogenesis; immune response; inflammatory response; chemotaxis; signal transduction; positive regulation of cell migration

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCL7 recombinant protein

Reference Product	PubMed Publications
CCL2 recombinant protein	>221 publications with CCL7 and CCL2
CCR2 recombinant protein	>84 publications with CCL7 and CCR2
CCL11 recombinant protein	>68 publications with CCL7 and CCL11
CCR3 recombinant protein	>43 publications with CCL7 and CCR3
CCR1 recombinant protein	>40 publications with CCL7 and CCR1
CCR5 recombinant protein	>34 publications with CCL7 and CCR5
CCL17 recombinant protein	>22 publications with CCL7 and CCL17
CCL22 recombinant protein	>20 publications with CCL7 and CCL22
CXCR3 recombinant protein	>9 publications with CCL7 and CXCR3
CCR10 recombinant protein	>3 publications with CCL7 and CCR10

Diseases associated with CCL7 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>159 publications with CCL7 and Inflammation
Lung Diseases Antibodies	>53 publications with CCL7 and Lung Diseases
Hypersensitivity Antibodies	>52 publications with CCL7 and Hypersensitivity
Necrosis Antibodies	>45 publications with CCL7 and Necrosis
Disease Models, Animal Antibodies	>41 publications with CCL7 and Disease Models, Animal
Neoplasms Antibodies	>40 publications with CCL7 and Neoplasms
Fibrosis Antibodies	>20 publications with CCL7 and Fibrosis
Cardiovascular Diseases Antibodies	>18 publications with CCL7 and Cardiovascular Diseases
Atherosclerosis Antibodies	>13 publications with CCL7 and Atherosclerosis
Liver Diseases Antibodies	>10 publications with CCL7 and Liver Diseases

Organs/Tissues associated with CCL7 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>246 publications with CCL7 and Blood
Lung Antibodies	>64 publications with CCL7 and Lung
Skin Antibodies	>29 publications with CCL7 and Skin
Intestine Antibodies	>14 publications with CCL7 and Intestine
Uterus Antibodies	>9 publications with CCL7 and Uterus
Placenta Antibodies	>4 publications with CCL7 and Placenta