Human CD57 Recombinant Protein – Cat# MBS141409

CD57 Human Recombinant Protein

Name: CD57 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS141409
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS141409

Introduction: CD57 also called B3GAT1is part of the glucuronyltransferase gene family. CD57 exhibits strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. CD57 takes part in the glucuronyl transfer reaction during… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD57, Recombinant Protein

Full Product Name

Recombinant Human CD57

Product Gene Name

CD57 recombinant protein

Product Synonym Names

B3GAT1; CD57; GLCATP; GLCUATP; HNK1; LEU7; NK-1; NK1; Beta-1; 3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1; 3-glucuronyltransferase; GlcUAT-P; CD57 Human; CD57 Human Recombinant

Sequence

Amino acid: ADPTLAPLLA VHKDEGSDPR RETPPGADPR EYCTSDRDIV EVVRTEYVYT RPPPWSDTLP TIHVVTPTYS RPVQKAELTR MANTLLHVPN LHWLVVEDAP RRTPLTARLL RDTGLNYTHL HVETPRNYKL RGDARDPRIP RGTMQRNLAL RWLRETFPRN SSQPGVVYFA DDDNTYSLEL FEEMRSTRRV SVWPVAFVGG LRYEAPRVNG AGKVVGWKTV FDPHRPFAID MAGFAVNLRL ILQRSQAYFK LRGVKGGYQE SSLLRELVTL NDLEPKAANC TKILVWHTRT EKPVLVNEGK KGFTDPSVEI LEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL ngKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH.

Host

Sf9, Baculovirus Cells

Form/Format

Sterile filtered colorless solution.
The CD57 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 10% glycerol and 0.1M NaCl.

Purity/Purification

>90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

OMIM

AB029396 mRNA

3D Structure

ModBase 3D Structure for Q9P2W7

Product Categories/Family for CD57 recombinant protein

RECOMBINANT & NATURAL PROTEINS

Other Notes

Small volumes of CD57 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD57 purchase

MBS141409 is a recombinant protein targeting CD57. Also known as Recombinant Human CD57. Host: Sf9, Baculovirus Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for CD57. It may not necessarily be applicable to this product.

NCBI GI #

77695914

NCBI GeneID

27087

NCBI Accession #

NP_061114.2

UniProt Primary Accession #

Q9P2W7

UniProt Related Accession #

Q9P2W7

GenBank Nucleotide #

NP_061114.2

NCBI Official Full Name

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 isoform 1

NCBI Official Synonym Full Names

beta-1,3-glucuronyltransferase 1

NCBI Official Symbol

B3GAT1

NCBI Official Synonym Symbols

NK1; CD57; HNK1; LEU7; NK-1; GLCATP; GLCUATP

UniProt Protein Name

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

UniProt Synonym Protein Names

Beta-1,3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P

UniProt Gene Name

B3GAT1

UniProt Synonym Gene Names

GlcUAT-P

NCBI Protein Information

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

NCBI Summary for CD57

The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

UniProt Comments for CD57

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.

Research Articles on CD57

1. The study of CD57 antigen in blood lymphocytes is a useful marker that could cooperate in the diagnosis of chronic fatigue syndrome patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CD57 recombinant protein

Products by Pathway	Pathway Diagram
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies	A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
Defective B3GAT3 Causes JDSSDHD Pathway antibodies	Defective B3GAT3 Causes JDSSDHD Pathway Diagram
Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway antibodies	Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway Diagram
Defective B4GALT7 Causes EDS, Progeroid Type Pathway antibodies	Defective B4GALT7 Causes EDS, Progeroid Type Pathway Diagram
Defective CHST14 Causes EDS, Musculocontractural Type Pathway antibodies	Defective CHST14 Causes EDS, Musculocontractural Type Pathway Diagram
Defective CHST3 Causes SEDCJD Pathway antibodies	Defective CHST3 Causes SEDCJD Pathway Diagram
Defective CHST6 Causes MCDC1 Pathway antibodies	Defective CHST6 Causes MCDC1 Pathway Diagram
Defective CHSY1 Causes TPBS Pathway antibodies	Defective CHSY1 Causes TPBS Pathway Diagram
Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway antibodies	Defective EXT1 Causes Exostoses 1, TRPS2 And CHDS Pathway Diagram

Diseases associated with CD57 recombinant protein

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>1 publications with CD57 and Congenital Abnormalities
Prenatal Injuries Antibodies	>1 publications with CD57 and Prenatal Injuries
Prenatal Exposure Delayed Effects Antibodies	>1 publications with CD57 and Prenatal Exposure Delayed Effects
Necrosis Antibodies	>1 publications with CD57 and Necrosis

Organs/Tissues associated with CD57 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>5 publications with CD57 and Brain
Nerve Antibodies	>4 publications with CD57 and Nerve
Blood Antibodies	>2 publications with CD57 and Blood