Mouse CFD Recombinant Protein – Cat# MBS956431

Complement Factor D (CFD) Mouse Recombinant Protein

Name: CFD Recombinant Protein; Complement Factor D; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS956431
Price: 900 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS956431

This protein is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted… More details

$900 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Complement factor D (Cfd), Recombinant Protein

Full Product Name

Recombinant Mouse Complement factor D (Cfd)

Product Gene Name

Cfd recombinant protein

Sequence

ILGGQEAAAH ARPYMASVQV NGTHVCGGTL LDEQWVLSAA HCMDGVTDDD SVQVLLGAHS LSAPEPYKRW YDVQSVVPHP GSRPDSLEDD LILFKLSQNA SLGPHVRPLP LQYEDKEVEP GTLCDVAGWG VVTHAGRRPD VLHQLRVSIM NRTTCNLRTY HDGVVTINMM CAESNRRDTC RGDSGSPLVC GDAVEGVVTW GSRVCGNGKK PGVYTRVSSY RMWIENITNG NMTS

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

27,986 Da

Sequence Positions

26-259, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P03953

Species

Mouse

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cfd recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cfd purchase

MBS956431 is a recombinant protein targeting Cfd. Also known as Recombinant Mouse Complement factor D (Cfd). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Cfd. It may not necessarily be applicable to this product.

NCBI GI #

632794820

NCBI GeneID

11537

NCBI Accession #

NP_001278844.1

UniProt Primary Accession #

P03953

UniProt Secondary Accession #

Q61280

UniProt Related Accession #

P03953

GenBank Nucleotide #

NM_001291915.2

NCBI Official Full Name

complement factor D isoform 2 preproprotein

NCBI Official Synonym Full Names

complement factor D (adipsin)

NCBI Official Symbol

Cfd

NCBI Official Synonym Symbols

DF; Adn

UniProt Protein Name

Complement factor D

UniProt Synonym Protein Names

28 kDa adipocyte protein; Adipsin; C3 convertase activator; Properdin factor D

Protein Family

Complement factor

UniProt Gene Name

Cfd

UniProt Synonym Gene Names

Adn; Df

NCBI Protein Information

complement factor D

NCBI Summary for Cfd

This gene encodes a serine protease that plays an important role in the alternative pathway of complement activation for pathogen recognition and elimination. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that in turn cleaves factor B in the complement pathway. This gene is expressed in adipocytes and the mature enzyme is secreted into the bloodstream. Mice lacking the encoded product cannot initiate alternative pathway of complement activation. [provided by RefSeq, Jul 2016]

UniProt Comments for Cfd

Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

Research Articles on Cfd

1. An essential role for Factor D in the ability of the liver to recover from acute toxic injury, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Cfd recombinant protein

Reference Product	PubMed Publications
Vwf recombinant protein	>2 publications with Cfd and Vwf

Pathways associated with Cfd recombinant protein

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Alternative Complement Activation Pathway antibodies	Alternative Complement Activation Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Initial Triggering Of Complement Pathway antibodies	Initial Triggering Of Complement Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with Cfd recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>463 publications with Cfd and Cardiovascular Diseases
Heart Diseases Antibodies	>134 publications with Cfd and Heart Diseases
Hyperplasia Antibodies	>35 publications with Cfd and Hyperplasia
Disease Models, Animal Antibodies	>23 publications with Cfd and Disease Models, Animal
Carcinoma Antibodies	>22 publications with Cfd and Carcinoma
Inflammation Antibodies	>20 publications with Cfd and Inflammation
Hypertension Antibodies	>20 publications with Cfd and Hypertension
Liver Diseases Antibodies	>14 publications with Cfd and Liver Diseases
Kidney Diseases Antibodies	>10 publications with Cfd and Kidney Diseases
Hypertrophy Antibodies	>9 publications with Cfd and Hypertrophy

Organs/Tissues associated with Cfd recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>829 publications with Cfd and Blood
Other Antibodies	>314 publications with Cfd and Other
Lung Antibodies	>124 publications with Cfd and Lung
Muscle Antibodies	>35 publications with Cfd and Muscle
Joint Antibodies	>31 publications with Cfd and Joint
Eye Antibodies	>28 publications with Cfd and Eye
Skin Antibodies	>27 publications with Cfd and Skin
Kidney Antibodies	>13 publications with Cfd and Kidney
Thyroid Antibodies	>11 publications with Cfd and Thyroid
Embryonic Tissue Antibodies	>8 publications with Cfd and Embryonic Tissue