Human DLL1 Recombinant Protein – Cat# MBS8304970

DLL1 Human Recombinant Protein

Name: DLL1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS8304970
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8304970

Recombinant Human DLL1 Protein is produced by mammalian expression system and the target gene encoding Gln18-Gly540 is expressed More details

$285 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DLL1, Recombinant Protein

Full Product Name

Recombinant Human DLL1 Protein

Product Gene Name

DLL1 recombinant protein

Product Synonym Names

Delta-like protein 1; Drosophila Delta homolog 1; Delta1; H-Delta-1

Sequence

QVWSSGVFEL KLQEFVNKKG LLGNRNCCRG GAGPPPCACR TFFRVCLKHY QASVSPEPPC TYGSAVTPVL GVDSFSLPDG GGADSAFSNP IRFPFGFTWP GTFSLIIEAL HTDSPDDLAT ENPERLISRL ATQRHLTVGE EWSQDLHSSG RTDLKYSYRF VCDEHYYGEG CSVFCRPRDD AFGHFTCGER GEKVCNPGWK GPYCTEPICL PGCDEQHGFC DKPGECKCRV GWQGRYCDEC IRYPGCLHGT CQQPWQCNCQ EGWGGLFCNQ DLNYCTHHKP CKNGATCTNT GQGSYTCSCR PGYTGATCEL GIDECDPSPC KNGGSCTDLE NSYSCTCPPG FYGKICELSA MTCADGPCFN GGRCSDSPDG GYSCRCPVGY SGFNCEKKID YCSSSPCSNG AKCVDLGDAY LCRCQAGFSG RHCDDNVDDC ASSPCANGGT CRDGVNDFSC TCPPGYTGRN CSAPVSRCEH APCHNGATCH ERGHRYVCEC ARGYGGPNCQ FLLPELPPGP AVVDLTEKLE GQGHHHHHH

Host

Human Cells

Form/Format

Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.

Purity/Purification

>95% as determined by reducing SDS-PAGE

Preparation and Storage

Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

OMIM

606582

3D Structure

ModBase 3D Structure for O00548

Endotoxin

Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Applications Tested/Suitable for DLL1 recombinant protein

ELISA (EIA), Western Blot (WB), SDS-PAGE

Other Notes

Small volumes of DLL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLL1 purchase

MBS8304970 is a recombinant protein targeting DLL1. Also known as Recombinant Human DLL1 Protein. Host: Human Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for DLL1. It may not necessarily be applicable to this product.

NCBI GI #

110735443

NCBI GeneID

28514

NCBI Accession #

NP_005609.3

UniProt Primary Accession #

O00548

UniProt Related Accession #

O00548

GenBank Nucleotide #

NP_005609.3

NCBI Official Full Name

delta-like protein 1

NCBI Official Synonym Full Names

delta like canonical Notch ligand 1

NCBI Official Symbol

DLL1

NCBI Official Synonym Symbols

DL1; Delta; DELTA1

UniProt Protein Name

Delta-like protein 1

UniProt Synonym Protein Names

Drosophila Delta homolog 1

Protein Family

Delta-like protein

UniProt Gene Name

DLL1

UniProt Synonym Gene Names

Delta1; H-Delta-1

UniProt Entry Name

DLL1_HUMAN

NCBI Protein Information

delta-like protein 1

NCBI Summary for DLL1

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

UniProt Comments for DLL1

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; cytoplasmic vesicle

Molecular Function: protein binding; calcium ion binding; Notch binding

Biological Process: regulation of cell adhesion; Notch signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; Notch receptor processing; cell fate determination; compartment specification; somite specification; cell-cell signaling; negative regulation of auditory receptor cell differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; heart looping; determination of left/right symmetry; cell differentiation; inner ear development; positive regulation of Notch signaling pathway

Research Articles on DLL1

1. DLL1-mediated Notch signaling promotes luminal breast cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DLL1 recombinant protein

Products by Pathway	Pathway Diagram
Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies	Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram
Breast Cancer Pathway antibodies	Breast Cancer Pathway Diagram
Breast Cancer Pathway antibodies	Breast Cancer Pathway Diagram
Canonical And Non-canonical Notch Signaling Pathway antibodies	Canonical And Non-canonical Notch Signaling Pathway Diagram
Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies	Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram
Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway antibodies	Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Of Signal Transduction Pathway antibodies	Diseases Of Signal Transduction Pathway Diagram