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EAF1 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1578023

MBS1578023 is a recombinant protein targeting EAF1. Also known as Recombinant Human EAF1 Protein, N-His-SUMO. Host: E coli. More details

$435 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EAF1, Recombinant Protein
Full Product Name
Recombinant Human EAF1 Protein, N-His-SUMO
Product Gene Name
Product Synonym Names
EAF1; ELL-associated factor 1
Host
E coli
Form/Format
Lyophilized from a solution in PBS pH7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity/Purification
>90% as determined by SDS-PAGE
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 degree C for twelve months from the date of receipt.
Molecular Weight
268
Sequence Positions
Gly19-Thr111
OMIM
608315
3D Structure
ModBase 3D Structure for Q96JC9
Species
Human
Reconstitution
Reconstitute in sterile water for a stock solution.

Product Categories/Family for EAF1 recombinant protein

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for EAF1 recombinant protein
SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

SDS-Page of EAF1 recombinant protein

SDS PAGE for Recombinant Human EAF1 protein
Human EAF1 Recombinant Protein – Cat# MBS1578023

Product References and Citations for EAF1 recombinant protein

ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation. PMID: 32087315
Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions. PMID: 36036574
Zebrafish eaf1 suppresses foxo3b expression to modulate transcriptional activity of gata1 and spi1 in primitive hematopoiesis. PMID: 24445282
Transcriptional factors Eaf1/2 inhibit endoderm and mesoderm formation via suppressing TGF-β signaling. PMID: 28887217
Eaf1 and Eaf2 negatively regulate canonical Wnt/β-catenin signaling. PMID: 23364330

Other Notes

Small volumes of EAF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EAF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ELL-associated factor 1
NCBI Official Synonym Full Names
ELL associated factor 1
NCBI Official Symbol
EAF1
UniProt Protein Name
ELL-associated factor 1
UniProt Gene Name
EAF1
UniProt Entry Name
EAF1_HUMAN
NCBI Protein Information
ELL-associated factor 1; ELL (eleven nineteen lysine-rich leukemia gene)-associated factor 1

UniProt Comments for EAF1

EAF1: Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Belongs to the EAF family.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: nucleoplasm; Cajal body; transcription elongation factor complex; cytoplasm; nuclear speck

Molecular Function: protein binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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