FGa Recombinant Protein – Cat# MBS2010572

Fibrinogen Alpha (FGa) Recombinant Protein

Name: FGa Recombinant Protein; Fibrinogen Alpha; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS2010572
Price: 200 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2010572

MBS2010572 is a recombinant protein targeting FGa. Also known as Recombinant Fibrinogen Alpha (FGa). Host: E Coli. More details

$200 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fibrinogen Alpha (FGa), Recombinant Protein

Full Product Name

Recombinant Fibrinogen Alpha (FGa)

Product Gene Name

FGa recombinant protein

Sequence

The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-EANQDF T NRINKLKNSL FDFQKNNKDS NSLTRNIMEY LRGDFANANN FDNTFGQVSE DLRRRIQILK RKVIEKAQQI QVLQKDVRDQ LIDMKRLEVD IDIKIRSCKG SCSRSVSREI NLKDYEGQQK QLEQVIAKDL LPAKDRQYLP AIKMSPVPDL VPGSFKSQLQ E

Host

E Coli

Form/Format

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

Purity/Purification

> 95%

Preparation and Storage

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Matching Pairs

Unconjugated Antibody: FGa (MBS2004077)
Immunogen: FGa (MBS2010572)

Matching Pairs

Biotin Conjugated Antibody: FGa (MBS2006069)
Immunogen: FGa (MBS2010572)

Molecular Weight

21.1kDa

Chromosome Location

Chromosome: 2; NC_005101.3 (201412182..201428346). Location: 2q34

3D Structure

ModBase 3D Structure for P06399

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Organism

Rattus norvegicus (Rat)

Expression System

Prokaryotic expression

Residues

Glu77~Glu244 (Accession # P06399) with N-terminal His-Tag

Endotoxin Level

<1.0EU per 1ug (determined by the LAL method)

Reconstitution

Reconstitute in sterile PBS, pH7.2-pH7.4.

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for FGa recombinant protein

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Other Notes

Small volumes of FGa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FGa. It may not necessarily be applicable to this product.

NCBI GI #

1706800

NCBI GeneID

361969

NCBI Accession #

P06399.3

UniProt Primary Accession #

P06399

UniProt Related Accession #

P06399

NCBI Official Full Name

Fibrinogen alpha chain

NCBI Official Synonym Full Names

fibrinogen alpha chain

NCBI Official Symbol

Fga

NCBI Official Synonym Symbols

Fba5e; Ac1873

UniProt Protein Name

Fibrinogen alpha chain

Protein Family

Fibrinogen

UniProt Gene Name

Fga

UniProt Entry Name

FIBA_RAT

NCBI Protein Information

fibrinogen alpha chain; fibrinogen, alpha polypeptide; fibrinogen, A alpha polypeptide

NCBI Summary for FGa

plays a role in blood coagulation; may be involved in liver regeneration [RGD, Feb 2006]

UniProt Comments for FGa

FGA: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cell surface; rough endoplasmic reticulum; fibrinogen complex; cytoplasm; cell cortex; vesicle; external side of plasma membrane

Molecular Function: protein binding, bridging; cell adhesion molecule binding; structural molecule activity; receptor binding

Biological Process: protein polymerization; platelet activation; positive regulation of heterotypic cell-cell adhesion; cell-matrix adhesion; response to morphine; signal transduction; response to estradiol stimulus; response to genistein; cellular protein complex assembly; positive regulation of protein secretion; positive regulation of vasoconstriction; acute-phase response; response to cycloheximide; innate immune response; response to calcium ion; blood coagulation; positive regulation of exocytosis

Research Articles on FGa

1. These results suggest that immunoreactivity of Fg in the kidney, as well as urinary excretion of Fg, serves as a sensitive and early diagnostic translational biomarker for detection of acute kidney injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FGa recombinant protein

Products by Pathway	Pathway Diagram
Amyloids Pathway antibodies	Amyloids Pathway Diagram
Blood Clotting Cascade Pathway antibodies	Blood Clotting Cascade Pathway Diagram
Common Pathway antibodies	Common Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies	Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway antibodies	GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram

Organs/Tissues associated with FGa recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>17 publications with FGa and Liver
Lung Antibodies	>16 publications with FGa and Lung
Kidney Antibodies	>9 publications with FGa and Kidney
Embryonic Tissue Antibodies	>5 publications with FGa and Embryonic Tissue
Spleen Antibodies	>3 publications with FGa and Spleen
Colon Antibodies	>1 publications with FGa and Colon